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The infundibular peptidergic neurons and glia cells in overeating, obesity, and diabetes. / Kalsbeek, Martin J. T.; Yi, Chun-Xia.

Handbook of Clinical Neurology. Vol. 180 Elsevier B.V., 2021. p. 315-325 (Handbook of Clinical Neurology; Vol. 180).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

Harvard

Kalsbeek, MJT & Yi, C-X 2021, The infundibular peptidergic neurons and glia cells in overeating, obesity, and diabetes. in Handbook of Clinical Neurology. vol. 180, Handbook of Clinical Neurology, vol. 180, Elsevier B.V., pp. 315-325. https://doi.org/10.1016/B978-0-12-820107-7.00019-7

APA

Kalsbeek, M. J. T., & Yi, C-X. (2021). The infundibular peptidergic neurons and glia cells in overeating, obesity, and diabetes. In Handbook of Clinical Neurology (Vol. 180, pp. 315-325). (Handbook of Clinical Neurology; Vol. 180). Elsevier B.V.. https://doi.org/10.1016/B978-0-12-820107-7.00019-7

Vancouver

Kalsbeek MJT, Yi C-X. The infundibular peptidergic neurons and glia cells in overeating, obesity, and diabetes. In Handbook of Clinical Neurology. Vol. 180. Elsevier B.V. 2021. p. 315-325. (Handbook of Clinical Neurology). doi: 10.1016/B978-0-12-820107-7.00019-7

Author

Kalsbeek, Martin J. T. ; Yi, Chun-Xia. / The infundibular peptidergic neurons and glia cells in overeating, obesity, and diabetes. Handbook of Clinical Neurology. Vol. 180 Elsevier B.V., 2021. pp. 315-325 (Handbook of Clinical Neurology).

BibTeX

@inbook{26b6d49113ae4fd19f4b4994720e21e0,
title = "The infundibular peptidergic neurons and glia cells in overeating, obesity, and diabetes",
abstract = "Dysfunctional regulation of energy homeostasis results in increased bodyweight and obesity, eventually leading to type 2 diabetes mellitus. The infundibular nucleus (IFN) of the hypothalamus is the main regulator of energy homeostasis. The peptidergic neurons and glia cells of the IFN receive metabolic cues concerning energy state of the body from the circulation. The IFN can monitor hormones like insulin and leptin and nutrients like glucose and fatty acids. All these metabolic cues are integrated into an output signal regulating energy homeostasis through the release of neuropeptides. These neuropeptides are released in several inter- and extrahypothalamic brain regions involved in regulation of energy homeostasis. This review will give an overview of the peripheral signals involved in the regulation of energy homeostasis, the peptidergic neurons and glial cells of the IFN, and will highlight the main intra-hypothalamic projection sites of the IFN.",
keywords = "Diabetes, Gut hormones, Insulin, Leptin, Neuropeptides, Obesity",
author = "Kalsbeek, {Martin J. T.} and Chun-Xia Yi",
note = "Publisher Copyright: {\textcopyright} 2021 Elsevier B.V.",
year = "2021",
month = jan,
day = "1",
doi = "10.1016/B978-0-12-820107-7.00019-7",
language = "English",
volume = "180",
series = "Handbook of Clinical Neurology",
publisher = "Elsevier B.V.",
pages = "315--325",
booktitle = "Handbook of Clinical Neurology",

}

RIS

TY - CHAP

T1 - The infundibular peptidergic neurons and glia cells in overeating, obesity, and diabetes

AU - Kalsbeek, Martin J. T.

AU - Yi, Chun-Xia

N1 - Publisher Copyright: © 2021 Elsevier B.V.

PY - 2021/1/1

Y1 - 2021/1/1

N2 - Dysfunctional regulation of energy homeostasis results in increased bodyweight and obesity, eventually leading to type 2 diabetes mellitus. The infundibular nucleus (IFN) of the hypothalamus is the main regulator of energy homeostasis. The peptidergic neurons and glia cells of the IFN receive metabolic cues concerning energy state of the body from the circulation. The IFN can monitor hormones like insulin and leptin and nutrients like glucose and fatty acids. All these metabolic cues are integrated into an output signal regulating energy homeostasis through the release of neuropeptides. These neuropeptides are released in several inter- and extrahypothalamic brain regions involved in regulation of energy homeostasis. This review will give an overview of the peripheral signals involved in the regulation of energy homeostasis, the peptidergic neurons and glial cells of the IFN, and will highlight the main intra-hypothalamic projection sites of the IFN.

AB - Dysfunctional regulation of energy homeostasis results in increased bodyweight and obesity, eventually leading to type 2 diabetes mellitus. The infundibular nucleus (IFN) of the hypothalamus is the main regulator of energy homeostasis. The peptidergic neurons and glia cells of the IFN receive metabolic cues concerning energy state of the body from the circulation. The IFN can monitor hormones like insulin and leptin and nutrients like glucose and fatty acids. All these metabolic cues are integrated into an output signal regulating energy homeostasis through the release of neuropeptides. These neuropeptides are released in several inter- and extrahypothalamic brain regions involved in regulation of energy homeostasis. This review will give an overview of the peripheral signals involved in the regulation of energy homeostasis, the peptidergic neurons and glial cells of the IFN, and will highlight the main intra-hypothalamic projection sites of the IFN.

KW - Diabetes

KW - Gut hormones

KW - Insulin

KW - Leptin

KW - Neuropeptides

KW - Obesity

UR - http://www.scopus.com/inward/record.url?scp=85109463772&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-820107-7.00019-7

DO - 10.1016/B978-0-12-820107-7.00019-7

M3 - Chapter

C2 - 34225937

VL - 180

T3 - Handbook of Clinical Neurology

SP - 315

EP - 325

BT - Handbook of Clinical Neurology

PB - Elsevier B.V.

ER -

ID: 18993264