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Recovery of right ventricular function and strain in patients with ST-segment elevation myocardial infarction and concurrent chronic total occlusion. / van Veelen, Anna; Elias, Joëlle; van Dongen, Ivo M. et al.

In: international journal of cardiovascular imaging, Vol. 38, No. 3, 03.2022, p. 631-641.

Research output: Contribution to journal › Article › Academic › peer-review

Harvard

van Veelen, A, Elias, J, van Dongen, IM, Hoebers, LPC, Claessen, BEPM, Ramunddal, T, Laanmets, P, Eriksen, E, van der Schaaf, RJ, Nijveldt, R, Henriques, JPS & Hirsch, A 2022, 'Recovery of right ventricular function and strain in patients with ST-segment elevation myocardial infarction and concurrent chronic total occlusion', international journal of cardiovascular imaging, vol. 38, no. 3, pp. 631-641. https://doi.org/10.1007/s10554-021-02423-9

APA

van Veelen, A., Elias, J., van Dongen, I. M., Hoebers, L. P. C., Claessen, B. E. P. M., Ramunddal, T., Laanmets, P., Eriksen, E., van der Schaaf, R. J., Nijveldt, R., Henriques, J. P. S., & Hirsch, A. (2022). Recovery of right ventricular function and strain in patients with ST-segment elevation myocardial infarction and concurrent chronic total occlusion. international journal of cardiovascular imaging, 38(3), 631-641. https://doi.org/10.1007/s10554-021-02423-9

Vancouver

van Veelen A, Elias J, van Dongen IM, Hoebers LPC, Claessen BEPM, Ramunddal T et al. Recovery of right ventricular function and strain in patients with ST-segment elevation myocardial infarction and concurrent chronic total occlusion. international journal of cardiovascular imaging. 2022 Mar;38(3):631-641. Epub 2021. doi: 10.1007/s10554-021-02423-9

Author

van Veelen, Anna ; Elias, Joëlle ; van Dongen, Ivo M. et al. / Recovery of right ventricular function and strain in patients with ST-segment elevation myocardial infarction and concurrent chronic total occlusion. In: international journal of cardiovascular imaging. 2022 ; Vol. 38, No. 3. pp. 631-641.

BibTeX

@article{2b0fe8a4c2b04b03ac649018432071c8,
title = "Recovery of right ventricular function and strain in patients with ST-segment elevation myocardial infarction and concurrent chronic total occlusion",
abstract = "The right ventricle (RV) is frequently involved in ST-segment elevation myocardial infarction (STEMI) when the culprit or concurrent chronic total occlusion (CTO) is located in the right coronary artery (RCA). We investigated RV function recovery in STEMI-patients with concurrent CTO. In EXPLORE, STEMI-patients with concurrent CTO were randomized to CTO percutaneous coronary intervention (PCI) or no CTO-PCI. We analyzed 174 EXPLORE patients with serial cardiovascular magnetic resonance imaging RV data (baseline and 4-month follow-up), divided into three groups: CTO-RCA (CTO in RCA, culprit in non-RCA; n = 89), IRA-RCA (infarct related artery [IRA] in RCA, CTO in non-RCA; n = 56), and no-RCA (culprit and CTO not in RCA; n = 29). Tricuspid annular plane systolic excursion (TAPSE), RV ejection fraction (RVEF), RV global longitudinal strain (GLS) and free wall longitudinal strain (FWLS) were measured. We found that RV strain and TAPSE improved in IRA-RCA and CTO-RCA (irrespective of CTO-PCI) at follow-up, but not in no-RCA. Only RV FWLS was different among groups at baseline, which was lower in IRA-RCA than no-RCA (− 26.0 ± 8.3% versus − 31.0 ± 6.4%, p = 0.006). Baseline RVEF, RV end-diastolic volume and TAPSE were associated with RVEF at 4 months. RV function parameters were not predictive of 4 year mortality, although RV GLS showed additional predictive value for New York Heart Association Classification > 1 at 4 months. In conclusion, RV parameters significantly improved in patients with acute or chronic RCA occlusion, but not in no-RCA patients. RV FWLS was the only RV parameter able to discriminate between acute ischemic and non-ischemic myocardium. Moreover, RV GLS was independently predictive for functional status.",
keywords = "Cardiovascular magnetic resonance, Chronic total occlusion, Right ventricle, ST-segment elevation myocardial infarction, Strain analysis",
author = "{van Veelen}, Anna and Jo{\"e}lle Elias and {van Dongen}, {Ivo M.} and Hoebers, {Loes P. C.} and Claessen, {Bimmer E. P. M.} and Truls Ramunddal and Peep Laanmets and Erlend Eriksen and {van der Schaaf}, {Ren{\'e} J.} and Robin Nijveldt and Henriques, {Jose P. S.} and Alexander Hirsch",
note = "Funding Information: The EXPLORE study was investigator-initiated and funded by the Academic Medical Center and by a research grant from Abbott Vascular. Publisher Copyright: {\textcopyright} 2021, The Author(s).",
year = "2022",
month = mar,
doi = "10.1007/s10554-021-02423-9",
language = "English",
volume = "38",
pages = "631--641",
journal = "international journal of cardiovascular imaging",
issn = "1569-5794",
publisher = "Springer Netherlands",
number = "3",

}

RIS

TY - JOUR

T1 - Recovery of right ventricular function and strain in patients with ST-segment elevation myocardial infarction and concurrent chronic total occlusion

AU - van Veelen, Anna

AU - Elias, Joëlle

AU - van Dongen, Ivo M.

AU - Hoebers, Loes P. C.

AU - Claessen, Bimmer E. P. M.

AU - Ramunddal, Truls

AU - Laanmets, Peep

AU - Eriksen, Erlend

AU - van der Schaaf, René J.

AU - Nijveldt, Robin

AU - Henriques, Jose P. S.

AU - Hirsch, Alexander

N1 - Funding Information: The EXPLORE study was investigator-initiated and funded by the Academic Medical Center and by a research grant from Abbott Vascular. Publisher Copyright: © 2021, The Author(s).

PY - 2022/3

Y1 - 2022/3

N2 - The right ventricle (RV) is frequently involved in ST-segment elevation myocardial infarction (STEMI) when the culprit or concurrent chronic total occlusion (CTO) is located in the right coronary artery (RCA). We investigated RV function recovery in STEMI-patients with concurrent CTO. In EXPLORE, STEMI-patients with concurrent CTO were randomized to CTO percutaneous coronary intervention (PCI) or no CTO-PCI. We analyzed 174 EXPLORE patients with serial cardiovascular magnetic resonance imaging RV data (baseline and 4-month follow-up), divided into three groups: CTO-RCA (CTO in RCA, culprit in non-RCA; n = 89), IRA-RCA (infarct related artery [IRA] in RCA, CTO in non-RCA; n = 56), and no-RCA (culprit and CTO not in RCA; n = 29). Tricuspid annular plane systolic excursion (TAPSE), RV ejection fraction (RVEF), RV global longitudinal strain (GLS) and free wall longitudinal strain (FWLS) were measured. We found that RV strain and TAPSE improved in IRA-RCA and CTO-RCA (irrespective of CTO-PCI) at follow-up, but not in no-RCA. Only RV FWLS was different among groups at baseline, which was lower in IRA-RCA than no-RCA (− 26.0 ± 8.3% versus − 31.0 ± 6.4%, p = 0.006). Baseline RVEF, RV end-diastolic volume and TAPSE were associated with RVEF at 4 months. RV function parameters were not predictive of 4 year mortality, although RV GLS showed additional predictive value for New York Heart Association Classification > 1 at 4 months. In conclusion, RV parameters significantly improved in patients with acute or chronic RCA occlusion, but not in no-RCA patients. RV FWLS was the only RV parameter able to discriminate between acute ischemic and non-ischemic myocardium. Moreover, RV GLS was independently predictive for functional status.

AB - The right ventricle (RV) is frequently involved in ST-segment elevation myocardial infarction (STEMI) when the culprit or concurrent chronic total occlusion (CTO) is located in the right coronary artery (RCA). We investigated RV function recovery in STEMI-patients with concurrent CTO. In EXPLORE, STEMI-patients with concurrent CTO were randomized to CTO percutaneous coronary intervention (PCI) or no CTO-PCI. We analyzed 174 EXPLORE patients with serial cardiovascular magnetic resonance imaging RV data (baseline and 4-month follow-up), divided into three groups: CTO-RCA (CTO in RCA, culprit in non-RCA; n = 89), IRA-RCA (infarct related artery [IRA] in RCA, CTO in non-RCA; n = 56), and no-RCA (culprit and CTO not in RCA; n = 29). Tricuspid annular plane systolic excursion (TAPSE), RV ejection fraction (RVEF), RV global longitudinal strain (GLS) and free wall longitudinal strain (FWLS) were measured. We found that RV strain and TAPSE improved in IRA-RCA and CTO-RCA (irrespective of CTO-PCI) at follow-up, but not in no-RCA. Only RV FWLS was different among groups at baseline, which was lower in IRA-RCA than no-RCA (− 26.0 ± 8.3% versus − 31.0 ± 6.4%, p = 0.006). Baseline RVEF, RV end-diastolic volume and TAPSE were associated with RVEF at 4 months. RV function parameters were not predictive of 4 year mortality, although RV GLS showed additional predictive value for New York Heart Association Classification > 1 at 4 months. In conclusion, RV parameters significantly improved in patients with acute or chronic RCA occlusion, but not in no-RCA patients. RV FWLS was the only RV parameter able to discriminate between acute ischemic and non-ischemic myocardium. Moreover, RV GLS was independently predictive for functional status.

KW - Cardiovascular magnetic resonance

KW - Chronic total occlusion

KW - Right ventricle

KW - ST-segment elevation myocardial infarction

KW - Strain analysis

UR - http://www.scopus.com/inward/record.url?scp=85115416819&partnerID=8YFLogxK

U2 - 10.1007/s10554-021-02423-9

DO - 10.1007/s10554-021-02423-9

M3 - Article

C2 - 34554368

VL - 38

SP - 631

EP - 641

JO - international journal of cardiovascular imaging

JF - international journal of cardiovascular imaging

SN - 1569-5794

IS - 3

ER -

ID: 19885843