Research output: Contribution to journal › Article › Academic › peer-review
No Evidence of Ntwetwe Virus Infections in Children Presenting to Kiboga Hospital, Uganda. / Edridge, Arthur W. D.; van den Brekel, Nathalie; Mukungu, Philly et al.
In: Tropical Medicine and Infectious Disease, Vol. 8, No. 1, 21, 01.01.2023.Research output: Contribution to journal › Article › Academic › peer-review
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TY - JOUR
T1 - No Evidence of Ntwetwe Virus Infections in Children Presenting to Kiboga Hospital, Uganda
AU - Edridge, Arthur W. D.
AU - van den Brekel, Nathalie
AU - Mukungu, Philly
AU - Nakayima, Rachael
AU - Bbosa, Samuel
AU - Isagara, Peter
AU - Boele van Hensbroek, Michael
AU - van der Hoek, Lia
AU - Kayiwa, John
AU - Lutwama, Julius J.
AU - Idro, Richard
N1 - Funding Information: This work was supported by an ESCMID Research Grant (to A.W.D.E), a grant from the Schumacher Kramer Foundation and a grant from PrimaGen Holding. Publisher Copyright: © 2022 by the authors.
PY - 2023/1/1
Y1 - 2023/1/1
N2 - We investigated whether Ntwetwe virus?a novel orthobunyavirus discovered in a Ugandan girl with a fatal encephalopathy?was a common reason for hospital admission for children to Kiboga hospital, Uganda. A case?control was conducted between September 2019 and September 2020, including cases with severe neurological disease and mild febrile illness, matched to a healthy control without fever. Among 143 subjects, no cases with an acute infection were identified. This result suggests that Ntwetwe virus does not cause a major burden of disease amongst children presenting to Kiboga hospital during the study period.
AB - We investigated whether Ntwetwe virus?a novel orthobunyavirus discovered in a Ugandan girl with a fatal encephalopathy?was a common reason for hospital admission for children to Kiboga hospital, Uganda. A case?control was conducted between September 2019 and September 2020, including cases with severe neurological disease and mild febrile illness, matched to a healthy control without fever. Among 143 subjects, no cases with an acute infection were identified. This result suggests that Ntwetwe virus does not cause a major burden of disease amongst children presenting to Kiboga hospital during the study period.
KW - CNS infection
KW - Uganda
KW - emerging infectious diseases
KW - orthobunyavirus
KW - pediatrics
KW - virus discovery
UR - http://www.scopus.com/inward/record.url?scp=85146895190&partnerID=8YFLogxK
U2 - 10.3390/tropicalmed8010021
DO - 10.3390/tropicalmed8010021
M3 - Article
C2 - 36668928
VL - 8
JO - Tropical Medicine and Infectious Disease
JF - Tropical Medicine and Infectious Disease
SN - 2414-6366
IS - 1
M1 - 21
ER -
ID: 31685435