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Multifocal squamous cell carcinoma arising in a Favre-Racouchot lesion - report of two cases and review of the literature. / Leeuwis-Fedorovich, Natalja E.; Starink, Markus; van der Wal, Allard C.

In: Journal of dermatological case reports, Vol. 9, No. 4, 2015, p. 103-106.

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Leeuwis-Fedorovich NE, Starink M, van der Wal AC. Multifocal squamous cell carcinoma arising in a Favre-Racouchot lesion - report of two cases and review of the literature. Journal of dermatological case reports. 2015;9(4):103-106. doi: 10.3315/jdcr.2015.1215

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Leeuwis-Fedorovich, Natalja E. ; Starink, Markus ; van der Wal, Allard C. / Multifocal squamous cell carcinoma arising in a Favre-Racouchot lesion - report of two cases and review of the literature. In: Journal of dermatological case reports. 2015 ; Vol. 9, No. 4. pp. 103-106.

BibTeX

@article{4ab67893db2b45c88794b6cb3d03309f,
title = "Multifocal squamous cell carcinoma arising in a Favre-Racouchot lesion - report of two cases and review of the literature",
abstract = "Background: Favre-Racouchot syndrome (nodular cutaneous elastosis with cysts and comedones) is a cutaneous disease characterized by coexistence of cysts, comedones and elastotic nodules in actinically damaged skin, typically on the face. Ultraviolet radiation plays a significant role in the development of the disease. Unilateral lesions have been described. Main observation: In this report we present two cases of squamous cell carcinoma arising in a unilateral Favre-Racouchot plaque. Both patients, fair-skinned, elderly, with impaired immune function developed large, deep invasive tumors with perineural extension. Conclusions: Squamous cell carcinomas of large size and prominent invasive growth developing in immunocompromised individuals carry poor prognosis with regard to recurrence rate and metastasis. Manifestations of malignancy as described in this report, indicate the importance of close follow-up of patients with Favre-Racouchot syndrome",
author = "Leeuwis-Fedorovich, {Natalja E.} and Markus Starink and {van der Wal}, {Allard C.}",
year = "2015",
doi = "10.3315/jdcr.2015.1215",
language = "English",
volume = "9",
pages = "103--106",
journal = "Journal of dermatological case reports",
issn = "1898-7249",
publisher = "Spejalisci Dermatolodzy",
number = "4",

}

RIS

TY - JOUR

T1 - Multifocal squamous cell carcinoma arising in a Favre-Racouchot lesion - report of two cases and review of the literature

AU - Leeuwis-Fedorovich, Natalja E.

AU - Starink, Markus

AU - van der Wal, Allard C.

PY - 2015

Y1 - 2015

N2 - Background: Favre-Racouchot syndrome (nodular cutaneous elastosis with cysts and comedones) is a cutaneous disease characterized by coexistence of cysts, comedones and elastotic nodules in actinically damaged skin, typically on the face. Ultraviolet radiation plays a significant role in the development of the disease. Unilateral lesions have been described. Main observation: In this report we present two cases of squamous cell carcinoma arising in a unilateral Favre-Racouchot plaque. Both patients, fair-skinned, elderly, with impaired immune function developed large, deep invasive tumors with perineural extension. Conclusions: Squamous cell carcinomas of large size and prominent invasive growth developing in immunocompromised individuals carry poor prognosis with regard to recurrence rate and metastasis. Manifestations of malignancy as described in this report, indicate the importance of close follow-up of patients with Favre-Racouchot syndrome

AB - Background: Favre-Racouchot syndrome (nodular cutaneous elastosis with cysts and comedones) is a cutaneous disease characterized by coexistence of cysts, comedones and elastotic nodules in actinically damaged skin, typically on the face. Ultraviolet radiation plays a significant role in the development of the disease. Unilateral lesions have been described. Main observation: In this report we present two cases of squamous cell carcinoma arising in a unilateral Favre-Racouchot plaque. Both patients, fair-skinned, elderly, with impaired immune function developed large, deep invasive tumors with perineural extension. Conclusions: Squamous cell carcinomas of large size and prominent invasive growth developing in immunocompromised individuals carry poor prognosis with regard to recurrence rate and metastasis. Manifestations of malignancy as described in this report, indicate the importance of close follow-up of patients with Favre-Racouchot syndrome

U2 - 10.3315/jdcr.2015.1215

DO - 10.3315/jdcr.2015.1215

M3 - Review article

C2 - 26848318

VL - 9

SP - 103

EP - 106

JO - Journal of dermatological case reports

JF - Journal of dermatological case reports

SN - 1898-7249

IS - 4

ER -

ID: 2834873