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Morphologic Mapping of the Sublingual Microcirculation in Healthy Volunteers. / Güven, G. ksel; Uz, Z. hre; Hilty, Matthias P. et al.

In: Journal of vascular research, Vol. 59, No. 4, 01.07.2022, p. 199-208.

Research output: Contribution to journalArticleAcademicpeer-review

Harvard

Güven, GK, Uz, ZH, Hilty, MP, Bilecenoǧlu, B, Akin, Ș, Ince, Y & Ince, C 2022, 'Morphologic Mapping of the Sublingual Microcirculation in Healthy Volunteers', Journal of vascular research, vol. 59, no. 4, pp. 199-208. https://doi.org/10.1159/000522394

APA

Güven, G. K., Uz, Z. H., Hilty, M. P., Bilecenoǧlu, B., Akin, Ș., Ince, Y., & Ince, C. (2022). Morphologic Mapping of the Sublingual Microcirculation in Healthy Volunteers. Journal of vascular research, 59(4), 199-208. https://doi.org/10.1159/000522394

Vancouver

Güven GK, Uz ZH, Hilty MP, Bilecenoǧlu B, Akin Ș, Ince Y et al. Morphologic Mapping of the Sublingual Microcirculation in Healthy Volunteers. Journal of vascular research. 2022 Jul 1;59(4):199-208. Epub 2022. doi: 10.1159/000522394

Author

Güven, G. ksel ; Uz, Z. hre ; Hilty, Matthias P. et al. / Morphologic Mapping of the Sublingual Microcirculation in Healthy Volunteers. In: Journal of vascular research. 2022 ; Vol. 59, No. 4. pp. 199-208.

BibTeX

@article{4765b24231c74626a24aa4f26945ac23,
title = "Morphologic Mapping of the Sublingual Microcirculation in Healthy Volunteers",
abstract = "Purpose: Monitoring the sublingual and oral microcirculation (SM-OM) using hand-held vital microscopes (HVMs) has provided valuable insight into the (patho)physiology of diseases. However, the microvascular anatomy in a healthy population has not been adequately described yet. Methods: Incident dark field-based HVM imaging was used to visualize the SM-OM. First, the SM was divided into four different fields; Field-a (between incisors-lingua), Field-b (between the canine-first premolar-lingua), Field-c (between the first-second premolar-lingua), Field-d (between the second molar-wisdom teeth-lingua). Second, we investigated the buccal area, lower and upper lip. Total/functional vessel density (TVD/FCD), focus depth (FD), small vessel mean diameters (SVMDs), and capillary tortuosity score (CTS) were compared between the areas. Results: Fifteen volunteers with a mean age of 29 ± 6 years were enrolled. No statistical difference was found between the sublingual fields in terms of TVD (p = 0.30), FCD (p = 0.38), and FD (p = 0.09). SVMD was similar in Field-a, Field-b, and Field-c (p = 0.20-0.30), and larger in Field-d (p < 0.01, p = 0.015). The CTS of the buccal area was higher than in the lips. Conclusion: The sublingual area has a homogenous distribution in TVD, FCD, FD, and SVMD. This study can be a description of the normal microvascular anatomy for future researches regarding microcirculatory assessment.",
keywords = "Capillary, IDF imaging, Mapping, Microcirculation, Sublingual",
author = "G{\"u}ven, {G. ksel} and Uz, {Z. hre} and Hilty, {Matthias P.} and Burak Bilecenoǧlu and Șakir Akin and Yasin Ince and Can Ince",
note = "Publisher Copyright: {\textcopyright} 2022 The Author(s).",
year = "2022",
month = jul,
day = "1",
doi = "10.1159/000522394",
language = "English",
volume = "59",
pages = "199--208",
journal = "Journal of vascular research",
issn = "1018-1172",
publisher = "S. Karger AG",
number = "4",

}

RIS

TY - JOUR

T1 - Morphologic Mapping of the Sublingual Microcirculation in Healthy Volunteers

AU - Güven, G. ksel

AU - Uz, Z. hre

AU - Hilty, Matthias P.

AU - Bilecenoǧlu, Burak

AU - Akin, Șakir

AU - Ince, Yasin

AU - Ince, Can

N1 - Publisher Copyright: © 2022 The Author(s).

PY - 2022/7/1

Y1 - 2022/7/1

N2 - Purpose: Monitoring the sublingual and oral microcirculation (SM-OM) using hand-held vital microscopes (HVMs) has provided valuable insight into the (patho)physiology of diseases. However, the microvascular anatomy in a healthy population has not been adequately described yet. Methods: Incident dark field-based HVM imaging was used to visualize the SM-OM. First, the SM was divided into four different fields; Field-a (between incisors-lingua), Field-b (between the canine-first premolar-lingua), Field-c (between the first-second premolar-lingua), Field-d (between the second molar-wisdom teeth-lingua). Second, we investigated the buccal area, lower and upper lip. Total/functional vessel density (TVD/FCD), focus depth (FD), small vessel mean diameters (SVMDs), and capillary tortuosity score (CTS) were compared between the areas. Results: Fifteen volunteers with a mean age of 29 ± 6 years were enrolled. No statistical difference was found between the sublingual fields in terms of TVD (p = 0.30), FCD (p = 0.38), and FD (p = 0.09). SVMD was similar in Field-a, Field-b, and Field-c (p = 0.20-0.30), and larger in Field-d (p < 0.01, p = 0.015). The CTS of the buccal area was higher than in the lips. Conclusion: The sublingual area has a homogenous distribution in TVD, FCD, FD, and SVMD. This study can be a description of the normal microvascular anatomy for future researches regarding microcirculatory assessment.

AB - Purpose: Monitoring the sublingual and oral microcirculation (SM-OM) using hand-held vital microscopes (HVMs) has provided valuable insight into the (patho)physiology of diseases. However, the microvascular anatomy in a healthy population has not been adequately described yet. Methods: Incident dark field-based HVM imaging was used to visualize the SM-OM. First, the SM was divided into four different fields; Field-a (between incisors-lingua), Field-b (between the canine-first premolar-lingua), Field-c (between the first-second premolar-lingua), Field-d (between the second molar-wisdom teeth-lingua). Second, we investigated the buccal area, lower and upper lip. Total/functional vessel density (TVD/FCD), focus depth (FD), small vessel mean diameters (SVMDs), and capillary tortuosity score (CTS) were compared between the areas. Results: Fifteen volunteers with a mean age of 29 ± 6 years were enrolled. No statistical difference was found between the sublingual fields in terms of TVD (p = 0.30), FCD (p = 0.38), and FD (p = 0.09). SVMD was similar in Field-a, Field-b, and Field-c (p = 0.20-0.30), and larger in Field-d (p < 0.01, p = 0.015). The CTS of the buccal area was higher than in the lips. Conclusion: The sublingual area has a homogenous distribution in TVD, FCD, FD, and SVMD. This study can be a description of the normal microvascular anatomy for future researches regarding microcirculatory assessment.

KW - Capillary

KW - IDF imaging

KW - Mapping

KW - Microcirculation

KW - Sublingual

UR - http://www.scopus.com/inward/record.url?scp=85127866026&partnerID=8YFLogxK

U2 - 10.1159/000522394

DO - 10.1159/000522394

M3 - Article

C2 - 35313312

VL - 59

SP - 199

EP - 208

JO - Journal of vascular research

JF - Journal of vascular research

SN - 1018-1172

IS - 4

ER -

ID: 23057837