Research output: Contribution to journal › Review article › Academic › peer-review
Long-term vs Short-term Therapy With Vitamin K Antagonists for Symptomatic Venous Thromboembolism. / Middeldorp, Saskia; Hutten, Barbara A.
In: JAMA, Vol. 314, No. 1, 2015, p. 72-73.Research output: Contribution to journal › Review article › Academic › peer-review
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TY - JOUR
T1 - Long-term vs Short-term Therapy With Vitamin K Antagonists for Symptomatic Venous Thromboembolism
AU - Middeldorp, Saskia
AU - Hutten, Barbara A.
PY - 2015
Y1 - 2015
N2 - CLINICAL QUESTION Is long-term (>= 3 months) vs short-term therapy with vitamin K antagonists (VKAs) associated with differences in the incidence of recurrent venous thromboembolism (VTE), major bleeding, and mortality in patients with symptomatic VTE? BOTTOM LINE Long-term treatment with VKAs is associated with a reduced risk for recurrent VTE and an increased risk for major bleeding compared with short-term treatment in patients with VTE, but is not associated with differences in mortality
AB - CLINICAL QUESTION Is long-term (>= 3 months) vs short-term therapy with vitamin K antagonists (VKAs) associated with differences in the incidence of recurrent venous thromboembolism (VTE), major bleeding, and mortality in patients with symptomatic VTE? BOTTOM LINE Long-term treatment with VKAs is associated with a reduced risk for recurrent VTE and an increased risk for major bleeding compared with short-term treatment in patients with VTE, but is not associated with differences in mortality
U2 - 10.1001/jama.2015.2693
DO - 10.1001/jama.2015.2693
M3 - Review article
C2 - 26151268
VL - 314
SP - 72
EP - 73
JO - JAMA
JF - JAMA
SN - 0098-7484
IS - 1
ER -
ID: 2649606