Standard

Intestinal microbiota and faecal transplantation as treatment modality for insulin resistance and type 2 diabetes mellitus. / Udayappan, S. D.; Hartstra, A. V.; Dallinga-Thie, G. M.; Nieuwdorp, M.

In: Clinical and experimental immunology, Vol. 177, No. 1, 2014, p. 24-29.

Research output: Contribution to journalReview articleAcademicpeer-review

Harvard

APA

Vancouver

Author

BibTeX

@article{f44969ffad544beda44e26e8cd48433e,
title = "Intestinal microbiota and faecal transplantation as treatment modality for insulin resistance and type 2 diabetes mellitus",
abstract = "The prevalence of obesity and diabetes mellitus type 2 is increasing rapidly around the globe. Recent insights have generated an entirely new perspective that the intestinal microbiota may play a significant role in the development of these metabolic disorders. Alterations in the intestinal microbiota composition promote systemic inflammation that is a hallmark of obesity and subsequent insulin resistance. Thus, it is important to understand the reciprocal relationship between intestinal microbiota composition and metabolic health in order to eventually prevent disease progression. In this respect, faecal transplantation studies have implicated that butyrate-producing intestinal bacteria are crucial in this process and be considered as key players in regulating diverse signalling cascades associated with human glucose and lipid metabolism",
author = "Udayappan, {S. D.} and Hartstra, {A. V.} and Dallinga-Thie, {G. M.} and M. Nieuwdorp",
year = "2014",
doi = "10.1111/cei.12293",
language = "English",
volume = "177",
pages = "24--29",
journal = "Clinical and experimental immunology",
issn = "0009-9104",
publisher = "Wiley-Blackwell",
number = "1",

}

RIS

TY - JOUR

T1 - Intestinal microbiota and faecal transplantation as treatment modality for insulin resistance and type 2 diabetes mellitus

AU - Udayappan, S. D.

AU - Hartstra, A. V.

AU - Dallinga-Thie, G. M.

AU - Nieuwdorp, M.

PY - 2014

Y1 - 2014

N2 - The prevalence of obesity and diabetes mellitus type 2 is increasing rapidly around the globe. Recent insights have generated an entirely new perspective that the intestinal microbiota may play a significant role in the development of these metabolic disorders. Alterations in the intestinal microbiota composition promote systemic inflammation that is a hallmark of obesity and subsequent insulin resistance. Thus, it is important to understand the reciprocal relationship between intestinal microbiota composition and metabolic health in order to eventually prevent disease progression. In this respect, faecal transplantation studies have implicated that butyrate-producing intestinal bacteria are crucial in this process and be considered as key players in regulating diverse signalling cascades associated with human glucose and lipid metabolism

AB - The prevalence of obesity and diabetes mellitus type 2 is increasing rapidly around the globe. Recent insights have generated an entirely new perspective that the intestinal microbiota may play a significant role in the development of these metabolic disorders. Alterations in the intestinal microbiota composition promote systemic inflammation that is a hallmark of obesity and subsequent insulin resistance. Thus, it is important to understand the reciprocal relationship between intestinal microbiota composition and metabolic health in order to eventually prevent disease progression. In this respect, faecal transplantation studies have implicated that butyrate-producing intestinal bacteria are crucial in this process and be considered as key players in regulating diverse signalling cascades associated with human glucose and lipid metabolism

U2 - 10.1111/cei.12293

DO - 10.1111/cei.12293

M3 - Review article

C2 - 24528224

VL - 177

SP - 24

EP - 29

JO - Clinical and experimental immunology

JF - Clinical and experimental immunology

SN - 0009-9104

IS - 1

ER -

ID: 2328968