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Incidence and risk factors of deep vein thrombosis after extracorporeal life support. / van Minnen, Olivier; van den Bergh, Walter M.; Droogh, Joep M. et al.

In: Artificial organs, Vol. 46, No. 9, 09.2022, p. 1893-1900.

Research output: Contribution to journalArticleAcademicpeer-review

Harvard

van Minnen, O, van den Bergh, WM, Droogh, JM, Koehorst, L, Lagrand, WK, Raasveld, SJ, Oude Lansink-Hartgring, A, Terpstra, A, Smit, JM, Tuinman, PR & Vlaar, APJ 2022, 'Incidence and risk factors of deep vein thrombosis after extracorporeal life support', Artificial organs, vol. 46, no. 9, pp. 1893-1900. https://doi.org/10.1111/aor.14271

APA

van Minnen, O., van den Bergh, W. M., Droogh, J. M., Koehorst, L., Lagrand, W. K., Raasveld, S. J., Oude Lansink-Hartgring, A., Terpstra, A., Smit, J. M., Tuinman, P. R., & Vlaar, A. P. J. (2022). Incidence and risk factors of deep vein thrombosis after extracorporeal life support. Artificial organs, 46(9), 1893-1900. https://doi.org/10.1111/aor.14271

Vancouver

Author

van Minnen, Olivier ; van den Bergh, Walter M. ; Droogh, Joep M. et al. / Incidence and risk factors of deep vein thrombosis after extracorporeal life support. In: Artificial organs. 2022 ; Vol. 46, No. 9. pp. 1893-1900.

BibTeX

@article{20f0e5b5bc00423196c9352471d8ed96,
title = "Incidence and risk factors of deep vein thrombosis after extracorporeal life support",
abstract = "Background: Deep vein thrombosis (DVT) after decannulation of extracorporeal life support (ECLS) is not uncommon. Moreover, the impact of anticoagulation and potential risk factors is unclear. Furthermore, it is unclear if cannula-associated DVT is more common in ECLS patients compared to critically ill patients without ECLS. Methods: All adult patients who were successfully weaned from ECLS and were screened for DVT following decannulation were included in this observational cohort study. The incidence of post-ECLS-DVT was assessed and the cannula-associated DVT rate was compared with that of patients without ECLS after central venous catheter (CVC) removal. The correlation between the level of anticoagulation, risk factors, and post-ECLS-DVT was determined. Results: We included 30 ECLS patients and 53 non-ECLS patients. DVT was found in 15 patients (50%) of which 10 patients had a DVT in a cannulated vein. No correlation between the level of anticoagulation and DVT was found. V-V ECLS mode was the only independent risk factor for post-ECLS-DVT (OR 5.5; 95%CI 1.16–26.41). We found no difference between the ECLS and non-ECLS cohorts regarding cannula-associated DVT rate (33% vs. 32%). Conclusion: Post-ECLS-DVT is a common finding that occurs in half of all patients supported with ECLS. The incidence of cannula-associated DVT was equal to CVC-associated DVT in critically ill patients without ECLS. V-V ECLS was an independent risk factor for post-ECLS-DVT.",
keywords = "anticoagulant, deep vein thrombosis, extracorporeal life support",
author = "{van Minnen}, Olivier and {van den Bergh}, {Walter M.} and Droogh, {Joep M.} and Lisette Koehorst and Lagrand, {Wim K.} and Raasveld, {S. Jorinde} and {Oude Lansink-Hartgring}, Annemieke and Aart Terpstra and Smit, {Jasper M.} and Tuinman, {Pieter R.} and Vlaar, {Alexander P. J.}",
note = "Publisher Copyright: {\textcopyright} 2022 The Authors. Artificial Organs published by International Center for Artificial Organ and Transplantation (ICAOT) and Wiley Periodicals LLC.",
year = "2022",
month = sep,
doi = "10.1111/aor.14271",
language = "English",
volume = "46",
pages = "1893--1900",
journal = "Artificial organs",
issn = "0160-564X",
publisher = "Wiley-Blackwell",
number = "9",

}

RIS

TY - JOUR

T1 - Incidence and risk factors of deep vein thrombosis after extracorporeal life support

AU - van Minnen, Olivier

AU - van den Bergh, Walter M.

AU - Droogh, Joep M.

AU - Koehorst, Lisette

AU - Lagrand, Wim K.

AU - Raasveld, S. Jorinde

AU - Oude Lansink-Hartgring, Annemieke

AU - Terpstra, Aart

AU - Smit, Jasper M.

AU - Tuinman, Pieter R.

AU - Vlaar, Alexander P. J.

N1 - Publisher Copyright: © 2022 The Authors. Artificial Organs published by International Center for Artificial Organ and Transplantation (ICAOT) and Wiley Periodicals LLC.

PY - 2022/9

Y1 - 2022/9

N2 - Background: Deep vein thrombosis (DVT) after decannulation of extracorporeal life support (ECLS) is not uncommon. Moreover, the impact of anticoagulation and potential risk factors is unclear. Furthermore, it is unclear if cannula-associated DVT is more common in ECLS patients compared to critically ill patients without ECLS. Methods: All adult patients who were successfully weaned from ECLS and were screened for DVT following decannulation were included in this observational cohort study. The incidence of post-ECLS-DVT was assessed and the cannula-associated DVT rate was compared with that of patients without ECLS after central venous catheter (CVC) removal. The correlation between the level of anticoagulation, risk factors, and post-ECLS-DVT was determined. Results: We included 30 ECLS patients and 53 non-ECLS patients. DVT was found in 15 patients (50%) of which 10 patients had a DVT in a cannulated vein. No correlation between the level of anticoagulation and DVT was found. V-V ECLS mode was the only independent risk factor for post-ECLS-DVT (OR 5.5; 95%CI 1.16–26.41). We found no difference between the ECLS and non-ECLS cohorts regarding cannula-associated DVT rate (33% vs. 32%). Conclusion: Post-ECLS-DVT is a common finding that occurs in half of all patients supported with ECLS. The incidence of cannula-associated DVT was equal to CVC-associated DVT in critically ill patients without ECLS. V-V ECLS was an independent risk factor for post-ECLS-DVT.

AB - Background: Deep vein thrombosis (DVT) after decannulation of extracorporeal life support (ECLS) is not uncommon. Moreover, the impact of anticoagulation and potential risk factors is unclear. Furthermore, it is unclear if cannula-associated DVT is more common in ECLS patients compared to critically ill patients without ECLS. Methods: All adult patients who were successfully weaned from ECLS and were screened for DVT following decannulation were included in this observational cohort study. The incidence of post-ECLS-DVT was assessed and the cannula-associated DVT rate was compared with that of patients without ECLS after central venous catheter (CVC) removal. The correlation between the level of anticoagulation, risk factors, and post-ECLS-DVT was determined. Results: We included 30 ECLS patients and 53 non-ECLS patients. DVT was found in 15 patients (50%) of which 10 patients had a DVT in a cannulated vein. No correlation between the level of anticoagulation and DVT was found. V-V ECLS mode was the only independent risk factor for post-ECLS-DVT (OR 5.5; 95%CI 1.16–26.41). We found no difference between the ECLS and non-ECLS cohorts regarding cannula-associated DVT rate (33% vs. 32%). Conclusion: Post-ECLS-DVT is a common finding that occurs in half of all patients supported with ECLS. The incidence of cannula-associated DVT was equal to CVC-associated DVT in critically ill patients without ECLS. V-V ECLS was an independent risk factor for post-ECLS-DVT.

KW - anticoagulant

KW - deep vein thrombosis

KW - extracorporeal life support

UR - http://www.scopus.com/inward/record.url?scp=85129374976&partnerID=8YFLogxK

U2 - 10.1111/aor.14271

DO - 10.1111/aor.14271

M3 - Article

C2 - 35466442

VL - 46

SP - 1893

EP - 1900

JO - Artificial organs

JF - Artificial organs

SN - 0160-564X

IS - 9

ER -

ID: 23380392