Research output: Contribution to journal › Review article › Academic › peer-review
Imaging fetal anatomy. / Dawood, Yousif; Buijtendijk, Marieke F. J.; Shah, Harsha et al.
In: Seminars in cell & developmental biology, Vol. 131, 11.2022, p. 78-92.Research output: Contribution to journal › Review article › Academic › peer-review
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TY - JOUR
T1 - Imaging fetal anatomy
AU - Dawood, Yousif
AU - Buijtendijk, Marieke F. J.
AU - Shah, Harsha
AU - Smit, Johannes A.
AU - Jacobs, Karl
AU - Hagoort, Jaco
AU - Oostra, Roelof-Jan
AU - Bourne, Tom
AU - van den Hoff, Maurice J. B.
AU - de Bakker, Bernadette S.
N1 - Funding Information: Yousif Dawood, Johannes A. Smit, Jaco Hagoort, Karl Jacobs, Roelof-Jan Oostra: none. Marieke F.J. Buijtendijk, Bernadette S. de Bakker and Maurice J.B. van den Hoff receive funding from a Dutch Top Sector Life Sciences & Health Consortium grant to investigate visualization of fetal anatomical structures by three-dimensional ultrasound. Samsung Medison (South Korea) supports the research in three-dimensional ultrasound through the loan of ultrasound equipment and partial coverage of the salary costs for the first year of the study. Marieke F.J. Buijtendijk received payment from NeuroLogica Corporation to present in a webinar on first trimester three-dimensional ultrasound imaging. Maurice J. B. van den Hoff is chair of the European Society of Cardiology, Working Group on Development, Anatomy and Pathology. Harsha Shah: receives honoraria for lecturing and research funding from Samsung Medison (South Korea). Tom Bourne receives honoraria for lecturing and research funding from Samsung Medison (South Korea), research support from Roche Diagnostics (Switzerland) and research support from Illumina, Inc (USA). He is supported by the NIHR Biomedical Research Center based at Imperial College Healthcare NHS Trust and Imperial College London. Funding Information: This study was supported in part by funding provided by the Amsterdam Reproduction and Development (AR&D) institute of Amsterdam UMC. AR&D had no role in the study design, data collection and analysis, preparation of the manuscript or decision to publish. Publisher Copyright: © 2022
PY - 2022/11
Y1 - 2022/11
N2 - Due to advancements in ultrasound techniques, the focus of antenatal ultrasound screening is moving towards the first trimester of pregnancy. The early first trimester however remains in part, a ‘black box’, due to the size of the developing embryo and the limitations of contemporary scanning techniques. Therefore there is a need for images of early anatomical developmental to improve our understanding of this area. By using new imaging techniques, we can not only obtain better images to further our knowledge of early embryonic development, but clear images of embryonic and fetal development can also be used in training for e.g. sonographers and fetal surgeons, or to educate parents expecting a child with a fetal anomaly. The aim of this review is to provide an overview of the past, present and future techniques used to capture images of the developing human embryo and fetus and provide the reader newest insights in upcoming and promising imaging techniques. The reader is taken from the earliest drawings of da Vinci, along the advancements in the fields of in utero ultrasound and MR imaging techniques towards high-resolution ex utero imaging using Micro-CT and ultra-high field MRI. Finally, a future perspective is given about the use of artificial intelligence in ultrasound and new potential imaging techniques such as synchrotron radiation-based CT to increase our knowledge regarding human development.
AB - Due to advancements in ultrasound techniques, the focus of antenatal ultrasound screening is moving towards the first trimester of pregnancy. The early first trimester however remains in part, a ‘black box’, due to the size of the developing embryo and the limitations of contemporary scanning techniques. Therefore there is a need for images of early anatomical developmental to improve our understanding of this area. By using new imaging techniques, we can not only obtain better images to further our knowledge of early embryonic development, but clear images of embryonic and fetal development can also be used in training for e.g. sonographers and fetal surgeons, or to educate parents expecting a child with a fetal anomaly. The aim of this review is to provide an overview of the past, present and future techniques used to capture images of the developing human embryo and fetus and provide the reader newest insights in upcoming and promising imaging techniques. The reader is taken from the earliest drawings of da Vinci, along the advancements in the fields of in utero ultrasound and MR imaging techniques towards high-resolution ex utero imaging using Micro-CT and ultra-high field MRI. Finally, a future perspective is given about the use of artificial intelligence in ultrasound and new potential imaging techniques such as synchrotron radiation-based CT to increase our knowledge regarding human development.
KW - Anatomy
KW - Development
KW - Embryonic
KW - Fetal
KW - Human
KW - Imaging
UR - http://www.scopus.com/inward/record.url?scp=85126108161&partnerID=8YFLogxK
U2 - 10.1016/j.semcdb.2022.02.023
DO - 10.1016/j.semcdb.2022.02.023
M3 - Review article
C2 - 35282997
VL - 131
SP - 78
EP - 92
JO - Seminars in cell & developmental biology
JF - Seminars in cell & developmental biology
SN - 1084-9521
ER -
ID: 22155406