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Effects of sterilization on the mechanical properties of poly(methyl methacrylate) based personalized medical devices. / On behalf of the CranioSafe Group.

In: Journal of the mechanical behavior of biomedical materials, Vol. 81, 2018, p. 168-172.

Research output: Contribution to journalArticleAcademicpeer-review

Harvard

On behalf of the CranioSafe Group 2018, 'Effects of sterilization on the mechanical properties of poly(methyl methacrylate) based personalized medical devices', Journal of the mechanical behavior of biomedical materials, vol. 81, pp. 168-172. https://doi.org/10.1016/j.jmbbm.2018.01.033

APA

On behalf of the CranioSafe Group (2018). Effects of sterilization on the mechanical properties of poly(methyl methacrylate) based personalized medical devices. Journal of the mechanical behavior of biomedical materials, 81, 168-172. https://doi.org/10.1016/j.jmbbm.2018.01.033

Vancouver

On behalf of the CranioSafe Group. Effects of sterilization on the mechanical properties of poly(methyl methacrylate) based personalized medical devices. Journal of the mechanical behavior of biomedical materials. 2018;81:168-172. doi: 10.1016/j.jmbbm.2018.01.033

Author

On behalf of the CranioSafe Group. / Effects of sterilization on the mechanical properties of poly(methyl methacrylate) based personalized medical devices. In: Journal of the mechanical behavior of biomedical materials. 2018 ; Vol. 81. pp. 168-172.

BibTeX

@article{414a152296a64851b52c50a6eea37fd9,
title = "Effects of sterilization on the mechanical properties of poly(methyl methacrylate) based personalized medical devices",
abstract = "Background: Nowadays, personalized medical devices are frequently used for patients. Due to the manufacturing procedure sterilization is required. How different sterilization methods affect the mechanical behavior of these devices is largely unknown. Materials and methods: Three poly(methyl methacrylate) (PMMA) based materials (Vertex Self-Curing, Palacos R+G, and NextDent C&B MFH) were sterilized with different sterilization methods: ethylene oxide, hydrogen peroxide gas plasma, autoclavation, and γ-irradiation. Mechanical properties were determined by testing the flexural strength, flexural modulus, fracture toughness, and impact strength. Results: The flexural strength of all materials was significantly higher after γ-irradiation compared to the control and other sterilization methods, as tested in a wet environment. NextDent C&B MFH showed the highest flexural and impact strength, Palacos R+G showed the highest maximum stress intensity factor and total fracture work. Conclusion: Autoclave sterilization is not suitable for the sterilization of PMMA-based materials. Ethylene oxide, hydrogen peroxide gas plasma, and γ-irradiation appear to be suitable techniques to sterilize PMMA-based personalized medical devices.",
author = "{On behalf of the CranioSafe Group} and M{\"u}nker, {T. J. A. G.} and {van de Vijfeijken}, {S. E. C. M.} and Mulder, {C. S.} and V. Vespasiano and Becking, {A. G.} and Kleverlaan, {C. J.} and Becking, {A. G.} and L. Dubois and Karssemakers, {L. H. E.} and Milstein, {D. M. J.} and {van de Vijfeijken}, {S. E. C. M.} and Depauw, {P. R. A. M.} and Hoefnagels, {F. W. A.} and Vandertop, {W. P.} and Kleverlaan, {C. J.} and M{\"u}nker, {T. J. A. G.} and Maal, {T. J. J.} and E. Nout and M. Riool and Zaat, {S. A. J.}",
year = "2018",
doi = "10.1016/j.jmbbm.2018.01.033",
language = "English",
volume = "81",
pages = "168--172",
journal = "Journal of the mechanical behavior of biomedical materials",
issn = "1751-6161",
publisher = "Elsevier BV",

}

RIS

TY - JOUR

T1 - Effects of sterilization on the mechanical properties of poly(methyl methacrylate) based personalized medical devices

AU - On behalf of the CranioSafe Group

AU - Münker, T. J. A. G.

AU - van de Vijfeijken, S. E. C. M.

AU - Mulder, C. S.

AU - Vespasiano, V.

AU - Becking, A. G.

AU - Kleverlaan, C. J.

AU - Becking, A. G.

AU - Dubois, L.

AU - Karssemakers, L. H. E.

AU - Milstein, D. M. J.

AU - van de Vijfeijken, S. E. C. M.

AU - Depauw, P. R. A. M.

AU - Hoefnagels, F. W. A.

AU - Vandertop, W. P.

AU - Kleverlaan, C. J.

AU - Münker, T. J. A. G.

AU - Maal, T. J. J.

AU - Nout, E.

AU - Riool, M.

AU - Zaat, S. A. J.

PY - 2018

Y1 - 2018

N2 - Background: Nowadays, personalized medical devices are frequently used for patients. Due to the manufacturing procedure sterilization is required. How different sterilization methods affect the mechanical behavior of these devices is largely unknown. Materials and methods: Three poly(methyl methacrylate) (PMMA) based materials (Vertex Self-Curing, Palacos R+G, and NextDent C&B MFH) were sterilized with different sterilization methods: ethylene oxide, hydrogen peroxide gas plasma, autoclavation, and γ-irradiation. Mechanical properties were determined by testing the flexural strength, flexural modulus, fracture toughness, and impact strength. Results: The flexural strength of all materials was significantly higher after γ-irradiation compared to the control and other sterilization methods, as tested in a wet environment. NextDent C&B MFH showed the highest flexural and impact strength, Palacos R+G showed the highest maximum stress intensity factor and total fracture work. Conclusion: Autoclave sterilization is not suitable for the sterilization of PMMA-based materials. Ethylene oxide, hydrogen peroxide gas plasma, and γ-irradiation appear to be suitable techniques to sterilize PMMA-based personalized medical devices.

AB - Background: Nowadays, personalized medical devices are frequently used for patients. Due to the manufacturing procedure sterilization is required. How different sterilization methods affect the mechanical behavior of these devices is largely unknown. Materials and methods: Three poly(methyl methacrylate) (PMMA) based materials (Vertex Self-Curing, Palacos R+G, and NextDent C&B MFH) were sterilized with different sterilization methods: ethylene oxide, hydrogen peroxide gas plasma, autoclavation, and γ-irradiation. Mechanical properties were determined by testing the flexural strength, flexural modulus, fracture toughness, and impact strength. Results: The flexural strength of all materials was significantly higher after γ-irradiation compared to the control and other sterilization methods, as tested in a wet environment. NextDent C&B MFH showed the highest flexural and impact strength, Palacos R+G showed the highest maximum stress intensity factor and total fracture work. Conclusion: Autoclave sterilization is not suitable for the sterilization of PMMA-based materials. Ethylene oxide, hydrogen peroxide gas plasma, and γ-irradiation appear to be suitable techniques to sterilize PMMA-based personalized medical devices.

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85042916019&origin=inward

UR - https://www.ncbi.nlm.nih.gov/pubmed/29524755

U2 - 10.1016/j.jmbbm.2018.01.033

DO - 10.1016/j.jmbbm.2018.01.033

M3 - Article

C2 - 29524755

VL - 81

SP - 168

EP - 172

JO - Journal of the mechanical behavior of biomedical materials

JF - Journal of the mechanical behavior of biomedical materials

SN - 1751-6161

ER -

ID: 5492484