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Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus—Does Sex Play a Role? / Gianakos, Arianna L.; Okedele, Olasumnbo; Mulcahey, Mary K. et al.
In: Journal of foot and ankle surgery, Vol. 62, No. 1, 01.01.2023, p. 96-101.

Research output: Contribution to journal › Article › Academic › peer-review

Harvard

Gianakos, AL, Okedele, O, Mulcahey, MK, Kerkhoffs, GM & Kennedy, JG 2023, 'Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus—Does Sex Play a Role?', Journal of foot and ankle surgery, vol. 62, no. 1, pp. 96-101. https://doi.org/10.1053/j.jfas.2022.05.005

APA

Gianakos, A. L., Okedele, O., Mulcahey, M. K., Kerkhoffs, G. M., & Kennedy, J. G. (2023). Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus—Does Sex Play a Role? Journal of foot and ankle surgery, 62(1), 96-101. https://doi.org/10.1053/j.jfas.2022.05.005

Vancouver

Gianakos AL, Okedele O, Mulcahey MK, Kerkhoffs GM, Kennedy JG. Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus—Does Sex Play a Role? Journal of foot and ankle surgery. 2023 Jan 1;62(1):96-101. Epub 2022. doi: 10.1053/j.jfas.2022.05.005

Author

Gianakos, Arianna L. ; Okedele, Olasumnbo ; Mulcahey, Mary K. et al. / Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus—Does Sex Play a Role?. In: Journal of foot and ankle surgery. 2023 ; Vol. 62, No. 1. pp. 96-101.

BibTeX

@article{e9b6fdd4e81a4265867722659ac34594,
title = "Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus—Does Sex Play a Role?",
abstract = "Autologous osteochondral transplantation (AOT) is used in the treatment of osteochondral lesions (OCL) of the talus. The purpose of this study was to compare the differences in the presentation of talar OCLs and outcomes following AOT between male and female patients. Eighty-seven consecutive patients, ages 16 to 65 years, who underwent AOT were retrospectively reviewed. Patients were divided into 2 groups based on sex. Demographic data and OCL defect characteristic data were recorded. Functional outcomes were assessed pre- and postoperatively using the Foot and Ankle Outcome Score (FAOS). The Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score was used to assess cartilage incorporation. Fifty-six (64%) males and 31 (36%) females with mean clinical follow-up of 47.2 months were included in this study. OCL defect size was significantly larger in male patients (112.8 mm2) when compared with female patients (88.7 mm2) (p < .001). Male patients presented with a lesion associated with a recognized trauma (p < .006) when compared with female patients who typically presented with associated chronic ankle instability. Mean FAOS improved pre- to postoperatively from 50 to 81 (p < .001) with a statistically significant increase found in male patients (p < .001). The mean MOCART score was 82.1 in male and 86.7 female patients (p < .001). Our study demonstrates potential gender-related differences in the presentation and mechanism of injury in the development of OCLs. It is also not unreasonable to suggest that there may also be differences in treatment and rehabilitation strategies to reduce the risk of developing OCLs in men and women.",
keywords = "3, autologous osteochondral transplantation, gender, osteochondral lesion, talus",
author = "Gianakos, {Arianna L.} and Olasumnbo Okedele and Mulcahey, {Mary K.} and Kerkhoffs, {Gino M.} and Kennedy, {John G.}",
note = "Funding Information: Sean Flynn for preliminary data collection and table formatting. Financial Disclosure: None reported. Conflict of Interest: Dr John G. Kennedy is a consultant for Arteriocyte, Inc and Arthrex Inc; is a board member for the International Society for Cartilage Repair of the Ankle, American Orthopaedic Foot and Ankle Society Awards and Scholarships Committee, International Cartilage Repair Society finance board. Dr Gino M.M.J. Kerkhoffs is a consultant for Arthrex Inc and is a board member of the International Society for Cartilage Repair of the Ankle. Dr Mary Mulcahey is a board member or member of the following: AAOS, American Journal of Sports Medicine Electronic Media, American Orthopaedic Association, American Orthopaedic Society for Sports Medicine, Arthroscopy, AANA, Ortho Info, RJOS, The Forum and a paid presenter for Arthrex, Inc. Dr Arianna Gianakos, Sean Flynn, and Okedele Olasunmbo have no conflicts to disclose. Publisher Copyright: {\textcopyright} 2022 the American College of Foot and Ankle Surgeons",
year = "2023",
month = jan,
day = "1",
doi = "10.1053/j.jfas.2022.05.005",
language = "English",
volume = "62",
pages = "96--101",
journal = "Journal of foot and ankle surgery",
issn = "1067-2516",
publisher = "Academic Press Inc.",
number = "1",

}

RIS

TY - JOUR

T1 - Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus—Does Sex Play a Role?

AU - Gianakos, Arianna L.

AU - Okedele, Olasumnbo

AU - Mulcahey, Mary K.

AU - Kerkhoffs, Gino M.

AU - Kennedy, John G.

N1 - Funding Information: Sean Flynn for preliminary data collection and table formatting. Financial Disclosure: None reported. Conflict of Interest: Dr John G. Kennedy is a consultant for Arteriocyte, Inc and Arthrex Inc; is a board member for the International Society for Cartilage Repair of the Ankle, American Orthopaedic Foot and Ankle Society Awards and Scholarships Committee, International Cartilage Repair Society finance board. Dr Gino M.M.J. Kerkhoffs is a consultant for Arthrex Inc and is a board member of the International Society for Cartilage Repair of the Ankle. Dr Mary Mulcahey is a board member or member of the following: AAOS, American Journal of Sports Medicine Electronic Media, American Orthopaedic Association, American Orthopaedic Society for Sports Medicine, Arthroscopy, AANA, Ortho Info, RJOS, The Forum and a paid presenter for Arthrex, Inc. Dr Arianna Gianakos, Sean Flynn, and Okedele Olasunmbo have no conflicts to disclose. Publisher Copyright: © 2022 the American College of Foot and Ankle Surgeons

PY - 2023/1/1

Y1 - 2023/1/1

N2 - Autologous osteochondral transplantation (AOT) is used in the treatment of osteochondral lesions (OCL) of the talus. The purpose of this study was to compare the differences in the presentation of talar OCLs and outcomes following AOT between male and female patients. Eighty-seven consecutive patients, ages 16 to 65 years, who underwent AOT were retrospectively reviewed. Patients were divided into 2 groups based on sex. Demographic data and OCL defect characteristic data were recorded. Functional outcomes were assessed pre- and postoperatively using the Foot and Ankle Outcome Score (FAOS). The Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score was used to assess cartilage incorporation. Fifty-six (64%) males and 31 (36%) females with mean clinical follow-up of 47.2 months were included in this study. OCL defect size was significantly larger in male patients (112.8 mm2) when compared with female patients (88.7 mm2) (p < .001). Male patients presented with a lesion associated with a recognized trauma (p < .006) when compared with female patients who typically presented with associated chronic ankle instability. Mean FAOS improved pre- to postoperatively from 50 to 81 (p < .001) with a statistically significant increase found in male patients (p < .001). The mean MOCART score was 82.1 in male and 86.7 female patients (p < .001). Our study demonstrates potential gender-related differences in the presentation and mechanism of injury in the development of OCLs. It is also not unreasonable to suggest that there may also be differences in treatment and rehabilitation strategies to reduce the risk of developing OCLs in men and women.

AB - Autologous osteochondral transplantation (AOT) is used in the treatment of osteochondral lesions (OCL) of the talus. The purpose of this study was to compare the differences in the presentation of talar OCLs and outcomes following AOT between male and female patients. Eighty-seven consecutive patients, ages 16 to 65 years, who underwent AOT were retrospectively reviewed. Patients were divided into 2 groups based on sex. Demographic data and OCL defect characteristic data were recorded. Functional outcomes were assessed pre- and postoperatively using the Foot and Ankle Outcome Score (FAOS). The Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score was used to assess cartilage incorporation. Fifty-six (64%) males and 31 (36%) females with mean clinical follow-up of 47.2 months were included in this study. OCL defect size was significantly larger in male patients (112.8 mm2) when compared with female patients (88.7 mm2) (p < .001). Male patients presented with a lesion associated with a recognized trauma (p < .006) when compared with female patients who typically presented with associated chronic ankle instability. Mean FAOS improved pre- to postoperatively from 50 to 81 (p < .001) with a statistically significant increase found in male patients (p < .001). The mean MOCART score was 82.1 in male and 86.7 female patients (p < .001). Our study demonstrates potential gender-related differences in the presentation and mechanism of injury in the development of OCLs. It is also not unreasonable to suggest that there may also be differences in treatment and rehabilitation strategies to reduce the risk of developing OCLs in men and women.

KW - 3

KW - autologous osteochondral transplantation

KW - gender

KW - osteochondral lesion

KW - talus

UR - http://www.scopus.com/inward/record.url?scp=85133292284&partnerID=8YFLogxK

U2 - 10.1053/j.jfas.2022.05.005

DO - 10.1053/j.jfas.2022.05.005

M3 - Article

C2 - 35753861

VL - 62

SP - 96

EP - 101

JO - Journal of foot and ankle surgery

JF - Journal of foot and ankle surgery

SN - 1067-2516

IS - 1

ER -

ID: 24986855