Advances in bronchoscopic optical coherence tomography and confocal laser endomicroscopy in pulmonary diseases

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Advances in bronchoscopic optical coherence tomography and confocal laser endomicroscopy in pulmonary diseases. / Kramer, Tess ; Wijsman, Pieta C.; Kalverda, Kirsten A. et al.

In: Current opinion in pulmonary medicine, Vol. 29, No. 1, 01.01.2023, p. 11-20.

Research output: Contribution to journal › Article › Academic › peer-review

BibTeX

@article{72e5238194f34ccfa7f46409d40fd73b,

title = "Advances in bronchoscopic optical coherence tomography and confocal laser endomicroscopy in pulmonary diseases",

abstract = "Purpose of reviewImaging techniques play a crucial role in the diagnostic work-up of pulmonary diseases but generally lack detailed information on a microscopic level. Optical coherence tomography (OCT) and confocal laser endomicroscopy (CLE) are imaging techniques which provide microscopic images in vivo during bronchoscopy. The purpose of this review is to describe recent advancements in the use of bronchoscopic OCT- and CLE-imaging in pulmonary medicine.Recent findingsIn recent years, OCT- and CLE-imaging have been evaluated in a wide variety of pulmonary diseases and demonstrated to be complementary to bronchoscopy for real-time, near-histological imaging. Several pulmonary compartments were visualized and characteristic patterns for disease were identified. In thoracic malignancy, OCT- and CLE-imaging can provide characterization of malignant tissue with the ability to identify the optimal sampling area. In interstitial lung disease (ILD), fibrotic patterns were detected by both (PS-) OCT and CLE, complementary to current HRCT-imaging. For obstructive lung diseases, (PS-) OCT enables to detect airway wall structures and remodelling, including changes in the airway smooth muscle and extracellular matrix.SummaryBronchoscopic OCT- and CLE-imaging allow high resolution imaging of airways, lung parenchyma, pleura, lung tumours and mediastinal lymph nodes. Although investigational at the moment, promising clinical applications are on the horizon.",

keywords = "bronchoscopy, confocal laser endomicroscopy, diagnostics, imaging, optical coherence tomography",

author = "Tess Kramer and Wijsman, {Pieta C.} and Kalverda, {Kirsten A.} and Bonta, {Peter I.} and Annema, {Jouke T.}",

note = "Funding Information: This review is author-initiated without industrial support. During the conduct of clinical studies, we received financial and material support for study purposes from Mauna Kea Technologies and Abbot (Abbott acquired St. Jude Medical). Furthermore, we received financial support from MedPhot (research program 00770372 with project number 00770384), which is partly financed by the Dutch Research Council (NWO). Publisher Copyright: {\textcopyright} 2023 Lippincott Williams and Wilkins. All rights reserved.",

year = "2023",

month = jan,

day = "1",

doi = "10.1097/MCP.0000000000000929",

language = "English",

volume = "29",

pages = "11--20",

journal = "Current opinion in pulmonary medicine",

issn = "1070-5287",

publisher = "Lippincott Williams and Wilkins",

number = "1",

}

RIS

TY - JOUR

T1 - Advances in bronchoscopic optical coherence tomography and confocal laser endomicroscopy in pulmonary diseases

AU - Kramer, Tess

AU - Wijsman, Pieta C.

AU - Kalverda, Kirsten A.

AU - Bonta, Peter I.

AU - Annema, Jouke T.

N1 - Funding Information: This review is author-initiated without industrial support. During the conduct of clinical studies, we received financial and material support for study purposes from Mauna Kea Technologies and Abbot (Abbott acquired St. Jude Medical). Furthermore, we received financial support from MedPhot (research program 00770372 with project number 00770384), which is partly financed by the Dutch Research Council (NWO). Publisher Copyright: © 2023 Lippincott Williams and Wilkins. All rights reserved.

PY - 2023/1/1

Y1 - 2023/1/1

N2 - Purpose of reviewImaging techniques play a crucial role in the diagnostic work-up of pulmonary diseases but generally lack detailed information on a microscopic level. Optical coherence tomography (OCT) and confocal laser endomicroscopy (CLE) are imaging techniques which provide microscopic images in vivo during bronchoscopy. The purpose of this review is to describe recent advancements in the use of bronchoscopic OCT- and CLE-imaging in pulmonary medicine.Recent findingsIn recent years, OCT- and CLE-imaging have been evaluated in a wide variety of pulmonary diseases and demonstrated to be complementary to bronchoscopy for real-time, near-histological imaging. Several pulmonary compartments were visualized and characteristic patterns for disease were identified. In thoracic malignancy, OCT- and CLE-imaging can provide characterization of malignant tissue with the ability to identify the optimal sampling area. In interstitial lung disease (ILD), fibrotic patterns were detected by both (PS-) OCT and CLE, complementary to current HRCT-imaging. For obstructive lung diseases, (PS-) OCT enables to detect airway wall structures and remodelling, including changes in the airway smooth muscle and extracellular matrix.SummaryBronchoscopic OCT- and CLE-imaging allow high resolution imaging of airways, lung parenchyma, pleura, lung tumours and mediastinal lymph nodes. Although investigational at the moment, promising clinical applications are on the horizon.

AB - Purpose of reviewImaging techniques play a crucial role in the diagnostic work-up of pulmonary diseases but generally lack detailed information on a microscopic level. Optical coherence tomography (OCT) and confocal laser endomicroscopy (CLE) are imaging techniques which provide microscopic images in vivo during bronchoscopy. The purpose of this review is to describe recent advancements in the use of bronchoscopic OCT- and CLE-imaging in pulmonary medicine.Recent findingsIn recent years, OCT- and CLE-imaging have been evaluated in a wide variety of pulmonary diseases and demonstrated to be complementary to bronchoscopy for real-time, near-histological imaging. Several pulmonary compartments were visualized and characteristic patterns for disease were identified. In thoracic malignancy, OCT- and CLE-imaging can provide characterization of malignant tissue with the ability to identify the optimal sampling area. In interstitial lung disease (ILD), fibrotic patterns were detected by both (PS-) OCT and CLE, complementary to current HRCT-imaging. For obstructive lung diseases, (PS-) OCT enables to detect airway wall structures and remodelling, including changes in the airway smooth muscle and extracellular matrix.SummaryBronchoscopic OCT- and CLE-imaging allow high resolution imaging of airways, lung parenchyma, pleura, lung tumours and mediastinal lymph nodes. Although investigational at the moment, promising clinical applications are on the horizon.

KW - bronchoscopy

KW - confocal laser endomicroscopy

KW - diagnostics

KW - imaging

KW - optical coherence tomography

UR - http://www.scopus.com/inward/record.url?scp=85143561153&partnerID=8YFLogxK

U2 - 10.1097/MCP.0000000000000929

DO - 10.1097/MCP.0000000000000929

M3 - Article

C2 - 36474462

VL - 29

SP - 11

EP - 20

JO - Current opinion in pulmonary medicine

JF - Current opinion in pulmonary medicine

SN - 1070-5287

IS - 1

ER -

ID: 28813039

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