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Co-display of diverse spike proteins on nanoparticles broadens sarbecovirus neutralizing antibody responses

Brinkkemper, M., Veth, T. S., Brouwer, P. J. M., Turner, H., Poniman, M., Burger, J. A., Bouhuijs, J. H., Olijhoek, W., Bontjer, I., Snitselaar, J. L., Caniels, T. G., van der Linden, C. A., Ravichandran, R., Villaudy, J., van der Velden, Y. U., Sliepen, K., van Gils, M. J., Ward, A. B., King, N. P., Heck, A. J. R., & 1 othersSanders, R. W., 22 Dec 2022, In: iScience. 25, 12, 105649.

Research output: Contribution to journal › Article › Academic › peer-review

A SARS-CoV-2 Wuhan spike virosome vaccine induces superior neutralization breadth compared to one using the Beta spike

van der Velden, Y. U., Grobben, M., Caniels, T. G., Burger, J. A., Poniman, M., Oomen, M., Rijnstra, E. S., Tejjani, K., Guerra, D., Kempers, R., Stegmann, T., van Gils, M. J. & Sanders, R. W., 1 Dec 2022, In: Scientific reports. 12, 1, 3884.

Research output: Contribution to journal › Article › Academic › peer-review

A third SARS-CoV-2 spike vaccination improves neutralization of variants-of-concern

Brinkkemper, M., Brouwer, P. J. M., Maisonnasse, P., Grobben, M., Caniels, T. G., Poniman, M., Burger, J. A., Bontjer, I., Oomen, M., Bouhuijs, J. H., van der Linden, C. A., Villaudy, J., van der Velden, Y. U., Sliepen, K., van Gils, M. J., le Grand, R. & Sanders, R. W., 1 Dec 2021, In: npj Vaccines. 6, 1, 146.

Research output: Contribution to journal › Article › Academic › peer-review

Early effects of htlv-1 infection on the activation, exhaustion, and differentiation of t-cells in humanized nsg mice

Espíndola, O. D. M., Rijnstra, E. S-V., Frankin, E., Weijer, K., van der Velden, Y. U., Berkhout, B., Blom, B. & Villaudy, J., 1 Oct 2021, In: Cells. 10, 10, 2514.

Research output: Contribution to journal › Article › Academic › peer-review

Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

Brouwer, P. J. M., Brinkkemper, M., Maisonnasse, P., Dereuddre-Bosquet, N., Grobben, M., Claireaux, M., de Gast, M., Marlin, R., Chesnais, V., Diry, S. G., Allen, J. D., Watanabe, Y., Giezen, J. M., Kerster, G., Turner, H. L., van der Straten, K., van der Linden, C. A., Aldon, Y., Naninck, T., Bontjer, I., & 27 othersBurger, J. A., Poniman, M., Mykytyn, A. Z., Okba, N. M. A., Schermer, E. E., van Breemen, M. J., Ravichandran, R., Caniels, T. G., van Schooten, J., Kahlaoui, N., Contreras, V., Lemaître, J., Chapon, C., Fang, R. H. T., Villaudy, J., Sliepen, K., van der Velden, Y. U., Haagmans, B. L., de Bree, G. J., Ginoux, E., Ward, A. B., Crispin, M., King, N. P., van der Werf, S., van Gils, M. J., le Grand, R. & Sanders, R. W., 4 Mar 2021, In: Cell. 184, 5, p. 1188-1200.e19 36 p., 365726.

Research output: Contribution to journal › Article › Academic › peer-review

Engineered miniature H1 promoters with dedicated RNA polymerase II or III activity

Gao, Z., van der Velden, Y. U., Fan, M., van der Linden, C. A., Vink, M., Herrera-Carrillo, E. & Berkhout, B., 1 Jan 2021, In: Journal of biological chemistry. 296, 100026.

Research output: Contribution to journal › Article › Academic › peer-review

Diverse HIV-1 escape pathways from broadly neutralizing antibody PGDM1400 in humanized mice

van der Velden, Y. U., Villaudy, J., Siteur - van Rijnstra, E., van der Linden, C. A., Vink, M. A., Schermer, E. E., Weijer, K., Berkhout, B., Sanders, R. W. & van Gils, M. J., 1 Jan 2020, In: mAbs. 12, 1, 1845908.

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Short Communication: Protective Efficacy of Broadly Neutralizing Antibody PGDM1400 Against HIV-1 Challenge in Humanized Mice

van der Velden, Y. U., Villaudy, J., Siteur-van Rijnstra, E., van der Linden, C. A., Frankin, E., Weijer, K., Schermer, E., Vink, M. A., Berkhout, B., Sanders, R. W. & van Gils, M. J., 2018, In: AIDS research and human retroviruses. 34, 9, p. 790-793

Research output: Contribution to journal › Article › Academic › peer-review

HIV-1 tolerates changes in A-count in a small segment of the pol gene

Klaver, B., van der Velden, Y., van Hemert, F., van der Kuyl, A. C. & Berkhout, B., 2017, In: Retrovirology. 14, 1, p. 43

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Construction of Nef-positive doxycycline-dependent HIV-1 variants using bicistronic expression elements

van der Velden, Y. U., Kleibeuker, W., Harwig, A., Klaver, B., Siteur-Van Rijnstra, E., Frankin, E., Berkhout, B. & Das, A. T., 2016, In: Virology. 488, p. 96-107

Research output: Contribution to journal › Article › Academic › peer-review