Research interests

The group of Wouter de Jonge studies mechanisms of functional and inflammatory gastro-intestinal disease.

-The pathogenesis of Inflammatory Bowel Diseases, through translational research and clinical trial analyses, including single cell sequencing and Mass Cytometry

-Preclinical research models for gastrointestinal Disease (IBD, irritable bowel syndrome (IBS), and motility disorders)

-Preclinical and Clinical research in surgical complications, wound healing and anastomotic healing

-Specialized medical nutrition to improve gut epithelial barriers and immunity - in alliance with industrial partners 

-Epigenetic aspects of cell differentiation in the gut in health and disease

A link to my papers:


A link to my group website for all details:

And UKBonn:


Group members:


Seppen J.E. PhD

te Velde A.A. PhD

van den Wijngaard R.M. PhD

Hakvoort T.B.M. PhD

Sovran B. PhD


PhD students:

Becker M.A.J. MD

Brinkman D.J. MD

Chen H.J. MD

Deianova N. MD

de Krijger M. MD

Eeftinck Schattenkerk L.D. MD

Elfiky A.M.I.M. MD

Ghiboub M. MSc

Hageman I.L. MD 

Joustra V.W. MD

Koopman N. Msc

Kreulen I.A.M. MSc

Luque Martin R.

Metselaar P.I. MSc

Peters E.G. MD

Pitotti G. MSc

Rahman S. MSc

ten Hove A.S. MD

van Helsdingen C.P.M. MD

van Thiel I.A.M. MSc

Wieser N.V. MSc

Fung I, Msc



Li Yim A.Y.F. MSc

Jan Verhoeff, Msc


Technical staff and facilies

Admiraal-van den Berg I. BSc

van Hamersveld H.P. BSc


Project and lab management: 

Verseijden C. BSc

Welting O. MSc





Mucosal Immunology, Neurogastroenterology

Research output

  1. Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation

    Research output: Contribution to journalArticleAcademicpeer-review

  2. Vagus nerve activity augments intestinal macrophage phagocytosis via nicotinic acetylcholine receptor alpha4beta2

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Neural reflex pathways in intestinal inflammation: hypotheses to viable therapy

    Research output: Contribution to journalReview articleAcademicpeer-review

  5. A new edge to immune surveillance by the neural system

    Research output: Contribution to journalEditorialAcademicpeer-review

View all (172) »

ID: 50064