Research interests

  • Developmental biology
  • Heart development
  • Transcriptional regulation
  • Epigenetics
  • Congenital heart defects
  • Conduction system
  • Sinoatrial node
  • Arrhythmias
  • Transgenic mice
  • Lineage analysis

specialisation

developmental biology, molecular biology, heart development

Research output

  1. EMERGE: a flexible modelling framework to predict genomic regulatory elements from genomic signatures

    Research output: Contribution to journal › Article › Academic › peer-review

  2. GATA-dependent regulatory switches establish atrioventricular canal specificity during heart development

    Research output: Contribution to journal › Article › Academic › peer-review

  3. A large permissive regulatory domain exclusively controls Tbx3 expression in the cardiac conduction system

    Research output: Contribution to journal › Article › Academic › peer-review

  4. Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice

    Research output: Contribution to journal › Article › Academic › peer-review

  5. Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer

    Research output: Contribution to journal › Article › Academic › peer-review

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Projects

  1. Christoffels V.M.: Transcriptional mechanism controlling of heart pacemaker and conduction system formation

    Project: Research

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