1. 2022
  2. ImmunoSep (Personalised Immunotherapy in Sepsis) international double-blind, double-dummy, placebo-controlled randomised clinical trial: study protocol

    Kotsaki, A., Pickkers, P., Bauer, M., Calandra, T., Lupse, M., Wiersinga, W. J., Meylan, S., Bloos, F., van der Poll, T., Slim, M. A., van Mourik, N., Müller, M. C. A., van Vught, L., Vlaar, A. P. J., de Nooijer, A., Bakkerus, L., Weis, S., Antonakos, N., Netea, M. G. & Giamarellos-Bourboulis, E. J., 20 Dec 2022, In: BMJ open. 12, 12, p. e067251

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Anti-C5a antibody vilobelimab treatment and the effect on biomarkers of inflammation and coagulation in patients with severe COVID-19: a substudy of the phase 2 PANAMO trial

    Lim, E. H. T., Vlaar, A. P. J., Bos, L. D. J., van Vught, L. A., Boer, A. M. T., Dujardin, R. W. G., Habel, M., Xu, Z., Brouwer, M. C., van de Beek, D., de Bruin, S., the Amsterdam UMC COVID-19 Biobank Investigators, van Agtmael, M., Algera, A. G., Appelman, B., van Baarle, F., Beudel, M., Bogaard, H. J., Bomers, M., Bonta, P., & 63 othersBotta, M., de Brabander, J., Bree, G., Bugiani, M., Bulle, E., Chouchane, O., Cloherty, A., Buis, D. T. P., de Rotte, M. C. F. J., Dijkstra, M., Dongelmans, D. A., Elbers, P., Fleuren, L., Geerlings, S., Geijtenbeek, T., Girbes, A., Goorhuis, B., Grobusch, M. P., Hagens, L., Hamann, J., Harris, V., Hemke, R., Hermans, S. M., Heunks, L., Hollmann, M., Horn, J., Hovius, J. W., de Jong, M. D., Koning, R., van Mourik, N., Nellen, J., Nossent, E. J., Paulus, F., Peters, E., Piña-Fuentes, D. A. I., van der Poll, T., Preckel, B., Prins, J. M., Raasveld, J., Reijnders, T., Schinkel, M., Schrauwen, F. A. P., Schultz, M. J., Schuurman, A., Schuurmans, J., Sigaloff, K., Slim, M. A., Smeele, P., Smit, M., Stijnis, C. S., Stilma, W., Teunissen, C., Thoral, P., Tsonas, A. M., Tuinman, P. R., van der Valk, M., Veelo, D., Volleman, C., de Vries, H., van Vugt, M., Wouters, D., Zwinderman, A. H. & Wiersinga, W. J., 1 Dec 2022, In: Respiratory research. 23, 1, 6 p., 375.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Association between age and the host response in critically ill patients with sepsis

    MARS consortium, 1 Dec 2022, In: Critical Care. 26, 1, 385.

    Research output: Contribution to journalArticleAcademicpeer-review

  5. Immunomodulation and endothelial barrier protection mediate the association between oral imatinib and mortality in hospitalised COVID-19 patients

    CounterCOVID study group, 1 Dec 2022, In: European respiratory journal. 60, 6, 2200780.

    Research output: Contribution to journalArticleAcademicpeer-review

  6. Myeloid DNA methyltransferase3b deficiency aggravates pulmonary fibrosis by enhancing profibrotic macrophage activation

    Qin, W., Spek, C. A., Scicluna, B. P., van der Poll, T. & Duitman, J., 1 Dec 2022, In: Respiratory research. 23, 1, 162.

    Research output: Contribution to journalArticleAcademicpeer-review

  7. Effect of erythromycin on mortality and the host response in critically ill patients with sepsis: a target trial emulation

    MARS consortium, Reijnders, T. D. Y., Peters-Sengers, H., van Vught, L. A., Uhel, F., Bonten, M. J. M., Cremer, O. L., Schultz, M. J., Stuiver, M. M. & van der Poll, T., Dec 2022, In: Critical care (London, England). 26, 1, p. 151 151.

    Research output: Contribution to journalArticleAcademicpeer-review

  8. Immunopathophysiology of human sepsis

    Wiersinga, W. J. & van der Poll, T., Dec 2022, In: EBioMedicine. 86, p. 104363

    Research output: Contribution to journalReview articleAcademicpeer-review

  9. Microglial cell response in α7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli

    Hoogland, I. C. M., Yik, J., Westhoff, D., Engelen-Lee, J-Y., Valls Seron, M., Man, W. K., Houben-Weerts, J. H. P. M., Tanck, M. W. T., van Westerloo, D. J., van der Poll, T., van Gool, W. A. & van de Beek, D., Dec 2022, In: Journal of neuroinflammation. 19, 1, p. 94 94.

    Research output: Contribution to journalArticleAcademicpeer-review

  10. Myeloid liver kinase B1 contributes to lung inflammation induced by lipoteichoic acid but not by viable Streptococcus pneumoniae

    Pereverzeva, L., Otto, N. A., Roelofs, J. J. T. H., de Vos, A. F. & van der Poll, T., Dec 2022, In: Respiratory research. 23, 1, p. 241 241.

    Research output: Contribution to journalArticleAcademicpeer-review

  11. Glucose metabolism is upregulated in the mononuclear cell proteome during sepsis and supports endotoxin-tolerant cell function

    Ferreira, B. L., Sousa, M. N. B., Leite, G. G. F., Brunialti, M. K. C., Nishiduka, E. S., Tashima, A. K., van der Poll, T. & Salomão, R., 18 Nov 2022, In: Frontiers in immunology. 13, 1051514.

    Research output: Contribution to journalArticleAcademicpeer-review

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