1. 2020
  2. Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism

    Loregger, A., Raaben, M., Nieuwenhuis, J., Tan, J. M. E., Jae, L. T., van den Hengel, L. G., Hendrix, S., van den Berg, M., Scheij, S., Song, J-Y., Huijbers, I. J., Kroese, L. J., Ottenhoff, R., van Weeghel, M., van de Sluis, B., Brummelkamp, T. & Zelcer, N., 2020, In : Nature communications. 11, 1, 1128.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. 2019
  4. The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1

    Herrera Moro Chao, D., Wang, Y., Foppen, E., Ottenhoff, R., van Roomen, C., Parlevliet, E. T., van Eijk, M., Verhoek, M., Boot, R., Marques, A. R., Scheij, S., Mirzaian, M., Kooijman, S., Jansen, K., Wang, D., Mergen, C., Seeley, R. J., Tschöp, M. H., Overkleeft, H., Rensen, P. C. N. & 3 others, Kalsbeek, A., Aerts, J. M. F. G. & Yi, C-X., 2019, In : Diabetes. 68, 12, p. 2223-2234

    Research output: Contribution to journalArticleAcademicpeer-review

  5. 2018
  6. HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution

    Tol, M. J., van der Lienden, M. J. C., Gabriel, T. L., Hagen, J. J., Scheij, S., Veenendaal, T., Klumperman, J., Donker-Koopman, W. E., Verhoeven, A. J., Overkleeft, H., Aerts, J. M., Argmann, C. A. & van Eijk, M., 2018, In : Autophagy. 14, 3, p. 437-449

    Research output: Contribution to journalArticleAcademicpeer-review

  7. Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice

    van Loon, N. M., Ottenhoff, R., Kooijman, S., Moeton, M., Scheij, S., Roscam Abbing, R. L. P., Gijbels, M. J. J., Levels, J. H. M., Sorrentino, V., Berbée, J. F. P., Rensen, P. C. N. & Zelcer, N., 2018, In : Arteriosclerosis, thrombosis, and vascular biology. 38, 8, p. 1785-1795

    Research output: Contribution to journalArticleAcademicpeer-review

  8. 2017
  9. A Specific Activity-Based Probe to Monitor Family GH59 Galactosylceramidase, the Enzyme Deficient in Krabbe Disease

    Marques, A. R. A., Willems, L. I., Herrera Moro, D., Florea, B. I., Scheij, S., Ottenhoff, R., van Roomen, C., Verhoek, M., Nelson, J. K., Kallemeijn, W. W., Biela-Banas, A., Martin, O. R., Cachón-González, M. B., Kim, N. N., Cox, T. M., Boot, R. G., Overkleeft, H. S. & Aerts, J. M. F. G., 2017, In : Chembiochem. 18, 4, p. 402-412

    Research output: Contribution to journalArticleAcademicpeer-review

  10. EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux

    Nelson, J. K., Koenis, D. S., Scheij, S., Cook, E. C. L., Moeton, M., Santos, A., Lobaccaro, J-M. A., Baron, S. & Zelcer, N., 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, 3, p. 423-432

    Research output: Contribution to journalArticleAcademicpeer-review

  11. Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis

    Loregger, A., Raaben, M., Tan, J., Scheij, S., Moeton, M., van den Berg, M., Gelberg-Etel, H., Stickel, E., Roitelman, J., Brummelkamp, T. & Zelcer, N., 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, 11, p. 2064-+

    Research output: Contribution to journalArticleAcademicpeer-review

  12. Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene

    Cook, E. C. L., Nelson, J. K., Sorrentino, V., Koenis, D., Moeton, M., Scheij, S., Ottenhoff, R., Bleijlevens, B., Loregger, A. & Zelcer, N., 2017, In : PLoS ONE. 12, 2, p. e0172721

    Research output: Contribution to journalArticleAcademicpeer-review

  13. Investigations on therapeutic glucocerebrosidases through paired detection with fluorescent activity-based probes

    Kallemeijn, W. W., Scheij, S., Hoogendoorn, S., Witte, M. D., Herrera Moro Chao, D., van Roomen, C. P. A. A., Ottenhoff, R., Overkleeft, H. S., Boot, R. G. & Aerts, J. M. F. G., 2017, In : PLoS ONE. 12, 2, p. e0170268

    Research output: Contribution to journalArticleAcademicpeer-review

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