Sander Tas

Research interests

My translational immunology research evolves around the overarching theme “The molecular regulation of inflammation”. Projects integrate basic immunological experiments, novel techniques and sampling of multiple tissues (translational medicine). Ultimate goals include development of new treatment strategies targeting (non-canonical) NF-κB signaling for immune-mediated inflammatory diseases (IMIDs).

Keywords: signal transduction pathways (i.e. NF-κB signaling), AIRE, rheumatoid arthritis, (rare) systemic autoimmune diseases including vasculitis, synovial inflammation, lymph node biology, immune cells, stromal cells, angiogenesis, gene therapy.

Participation in (inter)national consortia: ImmuneImage, DC4Balance, Joint Biology Consortium (Harvard/MIT), ARCAID, the Human Cell Atlas project.

Active member of various EULAR taskforces, EULAR synovitis study group (ESSG), and Standing Committee on Investigative Rheumatology (ESCIR).

specialisation

Internal Medicine-Rheumatology

Research output

Targeting of proangiogenic signalling pathways in chronic inflammation
Research output: Contribution to journal › Review article › Academic › peer-review
Tertiary Lymphoid Structures in Rheumatoid Arthritis: NF-κB-Inducing Kinase-Positive Endothelial Cells as Central Players
Research output: Contribution to journal › Article › Academic › peer-review
NF-κB-inducing kinase is a key regulator of inflammation-induced and tumour-associated angiogenesis
Research output: Contribution to journal › Article › Academic › peer-review
Non-canonical NF-κB signaling in rheumatoid arthritis: Dr Jekyll and Mr Hyde?
Research output: Contribution to journal › Review article › Academic › peer-review
Nuclear Factor-κB-inducing Kinase Is Expressed in Synovial Endothelial Cells in Patients with Early Arthritis and Correlates with Markers of Inflammation: A Prospective Cohort Study
Research output: Contribution to journal › Article › Academic › peer-review

Generic Portal

Research interests

specialisation

Research output

Targeting of proangiogenic signalling pathways in chronic inflammation

Tertiary Lymphoid Structures in Rheumatoid Arthritis: NF-κB-Inducing Kinase-Positive Endothelial Cells as Central Players

NF-κB-inducing kinase is a key regulator of inflammation-induced and tumour-associated angiogenesis

Non-canonical NF-κB signaling in rheumatoid arthritis: Dr Jekyll and Mr Hyde?

Nuclear Factor-κB-inducing Kinase Is Expressed in Synovial Endothelial Cells in Patients with Early Arthritis and Correlates with Markers of Inflammation: A Prospective Cohort Study

Projects

Tas S.W.: [NO DATA]