1. 2023
  2. Sterol-regulated transmembrane protein TMEM86a couples LXR signaling to regulation of lysoplasmalogens in macrophages

    van Wouw, S. A. E., van den Berg, M., el Ouraoui, M., Meurs, A., Kingma, J., Ottenhoff, R., Loix, M., Hoeksema, M. A., Prange, K., Pasterkamp, G., Hendriks, J. J. A., Bogie, J. F. J., van Klinken, J. B., Vaz, F. M., Jongejan, A., de Winther, M. P. J. & Zelcer, N., 1 Feb 2023, In: Journal of lipid research. 64, 2, p. 100325 1 p., 100325.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. 2021
  4. Four-and-a-half LIM domain protein 2 (FHL2) deficiency protects mice from diet-induced obesity and high FHL2 expression marks human obesity

    Clemente-Olivo, M. P., Habibe, J. J., Vos, M., Ottenhoff, R., Jongejan, A., Herrema, H., Zelcer, N., Kooijman, S., Rensen, P. C. N., van Raalte, D. H., Nieuwdorp, M., Eringa, E. C. & de Vries, C. J., 1 Aug 2021, In: Metabolism: clinical and experimental. 121, 154815.

    Research output: Contribution to journalArticleAcademicpeer-review

  5. Gcase and limp2 abnormalities in the liver of niemann pick type c mice

    van der Lienden, M. J. C., Aten, J., Marques, A. R. A., Waas, I. S. E., Larsen, P. W. B., Claessen, N., van der Wel, N. N., Ottenhoff, R., van Eijk, M. & Aerts, J. M. F. G., 1 Mar 2021, In: International journal of molecular sciences. 22, 5, p. 1-15 15 p., 2532.

    Research output: Contribution to journalArticleAcademicpeer-review

  6. Human glucocerebrosidase mediates formation of xylosylcholesterol by β-xylosidase and transxylosidase reactions

    Boer, D. E., Mirzaian, M., Ferraz, M. J., Zwiers, K. C., Baks, M. V., Hazeu, M. D., Ottenhoff, R., Marques, A. R. A., eijer, R., Roos, J. C. P., Cox, T. M., Boot, R. G., Pannu, N., Overkleeft, H. S., Artola, M. & Aerts, J. M., 2021, In: Journal of lipid research. 62, RA120001043.

    Research output: Contribution to journalArticleAcademicpeer-review

  7. 2020
  8. Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism

    Loregger, A., Raaben, M., Nieuwenhuis, J., Tan, J. M. E., Jae, L. T., van den Hengel, L. G., Hendrix, S., van den Berg, M., Scheij, S., Song, J-Y., Huijbers, I. J., Kroese, L. J., Ottenhoff, R., van Weeghel, M., van de Sluis, B., Brummelkamp, T. & Zelcer, N., 1 Dec 2020, In: Nature communications. 11, 1, 1128.

    Research output: Contribution to journalArticleAcademicpeer-review

  9. Regulation of intestinal LDLR by the LXR-IDOL axis

    van Loon, N. M., van Wouw, S. A. E., Ottenhoff, R., Nelson, J. K., Kingma, J., Scheij, S., Moeton, M. & Zelcer, N., 1 Dec 2020, In: Atherosclerosis. 315, p. 1-9 9 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  10. 2019
  11. The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1

    Herrera Moro Chao, D., Wang, Y., Foppen, E., Ottenhoff, R., van Roomen, C., Parlevliet, E. T., van Eijk, M., Verhoek, M., Boot, R., Marques, A. R., Scheij, S., Mirzaian, M., Kooijman, S., Jansen, K., Wang, D., Mergen, C., Seeley, R. J., Tschöp, M. H., Overkleeft, H., Rensen, P. C. N., & 3 othersKalsbeek, A., Aerts, J. M. F. G. & Yi, C-X., 2019, In: Diabetes. 68, 12, p. 2223-2234

    Research output: Contribution to journalArticleAcademicpeer-review

  12. 2018
  13. Chemical proteomic analysis of serine hydrolase activity in Niemann-Pick Type C mouse brain

    van Rooden, E. J., van Esbroeck, A. C. M., Baggelaar, M. P., Deng, H., Florea, B. I., Marques, A. R. A., Ottenhoff, R., Boot, R. G., Overkleeft, H. S., Aerts, J. M. F. G. & van der Stelt, M., 2018, In: Frontiers in neuroscience. 12, JUL, 440.

    Research output: Contribution to journalArticleAcademicpeer-review

  14. Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice

    van Loon, N. M., Ottenhoff, R., Kooijman, S., Moeton, M., Scheij, S., Roscam Abbing, R. L. P., Gijbels, M. J. J., Levels, J. H. M., Sorrentino, V., Berbée, J. F. P., Rensen, P. C. N. & Zelcer, N., 2018, In: Arteriosclerosis, thrombosis, and vascular biology. 38, 8, p. 1785-1795

    Research output: Contribution to journalArticleAcademicpeer-review

  15. 2017
  16. A Specific Activity-Based Probe to Monitor Family GH59 Galactosylceramidase, the Enzyme Deficient in Krabbe Disease

    Marques, A. R. A., Willems, L. I., Herrera Moro, D., Florea, B. I., Scheij, S., Ottenhoff, R., van Roomen, C., Verhoek, M., Nelson, J. K., Kallemeijn, W. W., Biela-Banas, A., Martin, O. R., Cachón-González, M. B., Kim, N. N., Cox, T. M., Boot, R. G., Overkleeft, H. S. & Aerts, J. M. F. G., 2017, In: Chembiochem. 18, 4, p. 402-412

    Research output: Contribution to journalArticleAcademicpeer-review

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