Research interests

  • The role of angiogenic and anti-angiogenic factors in ocular angiogenesis, particularly in AMD and diabetic retinopathy
  • The cellular mechanisms underlying loss of the blood-retinal barrier in diabetic retinopathy
  • Identification of new genes and mechanisms of angiogenesis
  • The role of complement activation and the proteasome in retinal pigment epithelium in the early stages of age-related macular degeneration
  • Prospective clinical trials on the use of anti-angiogenic therapy in AMD, diabetic retinopathy and retinal vein occlusions

See also: www.ocular-angiogenesis.nl/

specialisation

Ophthalmology

Research output

  1. CD34 marks angiogenic tip cells in human vascular endothelial cell cultures

    Research output: Contribution to journalArticleAcademicpeer-review

  2. The RESTORE Study Ranibizumab Monotherapy or Combined with Laser versus Laser Monotherapy for Diabetic Macular Edema

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus

    Research output: Contribution to journalArticleAcademicpeer-review

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