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  1. 2021

  2. Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease

    Lacy, M., Bürger, C., Shami, A., Ahmadsei, M., Winkels, H., Nitz, K., van Tiel, C. M., Seijkens, T. T. P., Kusters, P. J. H., Karshovka, E., Prange, K. H. M., Wu, Y., Brouns, S. L. N., Unterlugauer, S., Kuijpers, M. J. E., Reiche, M. E., Steffens, S., Edsfeldt, A., Megens, R. T. A., Heemskerk, J. W. M., & 5 othersGoncalves, I., Weber, C., Gerdes, N., Atzler, D. & Lutgens, E., 1 Dec 2021, In: Nature communications. 12, 1, 3754.

    Research output: Contribution to journal › Article › Academic › peer-review

  3. The CD40-CD40L Dyad as Immunotherapeutic Target in Cardiovascular Disease

    Bosmans, L. A., Bosch, L., Kusters, P. J. H., Lutgens, E. & Seijkens, T. T. P., Feb 2021, In: Journal of cardiovascular translational research. 14, 1, p. 13-22 10 p.

    Research output: Contribution to journal › Review article › Academic › peer-review

  4. 2020

  5. Immune Checkpoint Inhibitor Therapy Aggravates T Cell–Driven Plaque Inflammation in Atherosclerosis

    Poels, K., van Leent, M. M. T., Boutros, C., Tissot, H., Roy, S. V., Meerwaldt, A. E., Toner, Y. C. A., Reiche, M. E., Kusters, P. J. H., Malinova, T., Huveneers, S., Kaufman, A. E., Mani, V., Fayad, Z. A., de Winther, M. P. J., Marabelle, A., Mulder, W. J. M., Robert, C., Seijkens, T. T. P. & Lutgens, E., Nov 2020, In: JACC: CardioOncology. 2, 4, p. 599-610 12 p.

    Research output: Contribution to journal › Article › Academic › peer-review

  6. Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice

    Poels, K., van Leent, M. M. T., Reiche, M. E., Kusters, P. J. H., Huveneers, S., de Winther, M. P. J., Mulder, W. J. M., Lutgens, E. & Seijkens, T. T. P., 29 Aug 2020, In: Cells. 9, 9

    Research output: Contribution to journal › Article › Academic › peer-review

  7. Glucocorticoid-induced tumour necrosis factor receptor family-related protein (GITR) drives atherosclerosis in mice and is associated with an unstable plaque phenotype and cerebrovascular events in humans

    Shami, A., Atzler, D., Bosmans, L. A., Winkels, H., Meiler, S., Lacy, M., van Tiel, C., Ta Megens, R., Nitz, K., Baardman, J., Kusters, P., Seijkens, T., Buerger, C., Janjic, A., Riccardi, C., Edsfeldt, A., Monaco, C., Daemen, M., de Winther, M. P. J., Nilsson, J., & 4 othersWeber, C., Gerdes, N., Gonçalves, I. & Lutgens, E., 14 Aug 2020, In: European heart journal. 41, 31, p. 2938-2948 11 p.

    Research output: Contribution to journal › Article › Academic › peer-review

  8. 2019

  9. Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8 + T cell-mediated macrophage death

    Seijkens, T. T. P., Poels, K., Meiler, S., van Tiel, C. M., Kusters, P. J. H., Reiche, M., Atzler, D., Winkels, H., Tjwa, M., Poelman, H., Slütter, B., Kuiper, J., Gijbels, M., Kuivenhoven, J. A., Matic, L. P., Paulsson-Berne, G., Hedin, U., Hansson, G. R. K., Nicolaes, G. A. F., Daemen, M. J. A. P., & 4 othersWeber, C., Gerdes, N., de Winther, M. P. J. & Lutgens, E., 2019, In: European heart journal. 40, 4, p. 372-382

    Research output: Contribution to journal › Article › Academic › peer-review

  10. Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis

    Chen, P-Y., Qin, L., Li, G., Wang, Z., Dahlman, J. E., Malagon-Lopez, J., Gujja, S., Cilfone, N. A., Kauffman, K. J., Sun, L., Sun, H., Zhang, X., Aryal, B., Canfran-Duque, A., Liu, R., Kusters, P., Sehgal, A., Jiao, Y., Anderson, D. G., Gulcher, J., & 7 othersFernandez-Hernando, C., Lutgens, E., Schwartz, M. A., Pober, J. S., Chittenden, T. W., Tellides, G. & Simons, M., 2019, In: Nature Metabolism. 1, 9, p. 912-926

    Research output: Contribution to journal › Article › Academic › peer-review

  11. Evaluating the therapeutic potential of CD40 in low-grade chronic inflammation

    Kusters, P. J. H., 2019, 261 p.

    Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

  12. Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis

    Aarts, S. A. BM., Seijkens, T. T. P., Kusters, P. J. H., van Tiel, C. M., Reiche, M. E., den Toom, M., Beckers, L., van Roomen, C. P. AA., de Winther, M. P. J., Kooij, G. & Lutgens, E., 2019, In: Journal of pathology. 247, 4, p. 471-480

    Research output: Contribution to journal › Article › Academic › peer-review

  13. 2018

  14. CD40L deficiency protects against aneurysm formation

    Kusters, P. J. H., Seijkens, T. T. P., Beckers, L., Lievens, D., Winkels, H., de Waard, V., Duijvestijn, A., Liljeqvist, M. L., Roy, J., Daugherty, A., Newby, A., Gerdes, N. & Lutgens, E., 2018, In: Arteriosclerosis, thrombosis, and vascular biology. 38, 5, p. 1076-1085

    Research output: Contribution to journal › Article › Academic › peer-review

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