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- 2014
The E3 ubiquitin ligase MARCH6 degrades squalene monooxygenase and affects 3-hydroxy-3-methyl-glutaryl coenzyme A reductase and the cholesterol synthesis pathway
Zelcer, N., Sharpe, L. J., Loregger, A., Kristiana, I., Cook, E. C. L., Phan, L., Stevenson, J. & Brown, A. J., 2014, In: Molecular and cellular biology. 34, 7, p. 1262-1270Research output: Contribution to journal › Article › Academic › peer-review
The UPS and downs of cholesterol homeostasis
Sharpe, L. J., Cook, E. C. L., Zelcer, N. & Brown, A. J., 2014, In: Trends in biochemical sciences. 39, 11, p. 527-535Research output: Contribution to journal › Review article › Academic › peer-review
- 2013
Identification of a loss-of-function inducible degrader of the low-density lipoprotein receptor variant in individuals with low circulating low-density lipoprotein
Sorrentino, V., Fouchier, S. W., Motazacker, M. M., Nelson, J. K., Defesche, J. C., Dallinga-Thie, G. M., Kastelein, J. J. P., Kees Hovingh, G. & Zelcer, N., 2013, In: European heart journal. 34, 17, p. 1292-1297Research output: Contribution to journal › Article › Academic › peer-review
Myelin alters the inflammatory phenotype of macrophages by activating PPARs
Bogie, J. F. J., Jorissen, W., Mailleux, J., Nijland, P. G., Zelcer, N., Vanmierlo, T., van Horssen, J., Stinissen, P., Hellings, N. & Hendriks, J. J. A., 2013, In: Acta neuropathologica communications. 1, 1, p. 43-(13 p.)Research output: Contribution to journal › Article › Academic › peer-review
NDRG1 functions in LDL receptor trafficking by regulating endosomal recycling and degradation
Pietiäinen, V., Vassilev, B., Blom, T., Wang, W., Nelson, J., Bittman, R., Bäck, N., Zelcer, N. & Ikonen, E., 2013, In: Journal of cell science. 126, Part 17, p. 3961-3971Research output: Contribution to journal › Article › Academic › peer-review
The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation
Sorrentino, V., Nelson, J. K., Maspero, E., Marques, A. R. A., Scheer, L., Polo, S. & Zelcer, N., 2013, In: Journal of lipid research. 54, 8, p. 2174-2184Research output: Contribution to journal › Article › Academic › peer-review
- 2012
Advances in genetics show the need for extending screening strategies for autosomal dominant hypercholesterolaemia
Motazacker, M. M., Pirruccello, J., Huijgen, R., Do, R., Gabriel, S., Peter, J., Kuivenhoven, J. A., Defesche, J. C., Kastelein, J. J. P., Hovingh, G. K., Zelcer, N., Kathiresan, S. & Fouchier, S. W., 2012, In: European heart journal. 33, 11, p. 1360-1366Research output: Contribution to journal › Article › Academic › peer-review
A frameshift mutation in LRSAM1 is responsible for a dominant hereditary polyneuropathy
Weterman, M. A. J., Sorrentino, V., Kasher, P. R., Jakobs, M. E., van Engelen, B. G. M., Fluiter, K., de Wissel, M. B., Sizarov, A., Nürnberg, G., Nürnberg, P., Zelcer, N., Schelhaas, H. J. & Baas, F., 2012, In: Human molecular genetics. 21, 2, p. 358-370Research output: Contribution to journal › Article › Academic › peer-review
Fibroblast Growth Factor-21 (FGF21) Regulates Low-density Lipoprotein Receptor (LDLR) Levels in Cells via the E3-ubiquitin Ligase Mylip/Idol and the Canopy2 (Cnpy2)/Mylip-interacting Saposin-like Protein (Msap)
Do, H. T., Tselykh, T. V., Mäkelä, J., Ho, T. H., Olkkonen, V. M., Bornhauser, B. C., Korhonen, L., Zelcer, N. & Lindholm, D., 2012, In: Journal of biological chemistry. 287, 16, p. 12602-12611Research output: Contribution to journal › Article › Academic › peer-review
Post-transcriptional regulation of lipoprotein receptors by the E3-ubiquitin ligase inducible degrader of the low-density lipoprotein receptor
Sorrentino, V. & Zelcer, N., 2012, In: Current opinion in lipidology. 23, 3, p. 213-219Research output: Contribution to journal › Review article › Academic › peer-review
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