1. 2020
  2. Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site

    Martinelli, L., Adamopoulos, A., Johansson, P., Wan, P. T., Gunnarsson, J., Guo, H., Boyd, H., Zelcer, N. & Sixma, T. K., 25 Sept 2020, In: Journal of biological chemistry. 295, 39, p. 13570-13583 14 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. The MARCH6-SQLE Axis Controls Endothelial Cholesterol Homeostasis and Angiogenic Sprouting

    Tan, J. M. E., van der Stoel, M. M., van den Berg, M., van Loon, N. M., Moeton, M., Scholl, E., van der Wel, N. N., Kovačević, I., Hordijk, P. L., Loregger, A., Huveneers, S. & Zelcer, N., 4 Aug 2020, In: Cell reports. 32, 5, 107944.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain

    Bogie, J. F. J., Grajchen, E., Wouters, E., Corrales, A. G., Dierckx, T., Vanherle, S., Mailleux, J., Gervois, P., Wolfs, E., Dehairs, J., van Broeckhoven, J., Bowman, A. P., Lambrichts, I., Gustafsson, J-Å., Remaley, A. T., Mulder, M., Swinnen, J. V., Haidar, M., Ellis, S. R., Ntambi, J. M., & 2 othersZelcer, N. & Hendriks, J. J. A., 4 May 2020, In: Journal of experimental medicine. 217, 5, e20191660.

    Research output: Contribution to journalArticleAcademicpeer-review

  5. 2019
  6. FBXW7 regulates endothelial barrier function by suppression of the cholesterol synthesis pathway and prenylation of RhoB

    Pronk, M. C. A., Majolée, J., Loregger, A., van Bezu, J. S. M., Zelcer, N., Hordijk, P. L. & Kovačević, I., 2019, In: Molecular biology of the cell. 30, 5, p. 607-621

    Research output: Contribution to journalArticleAcademicpeer-review

  7. Industrial Trans Fatty Acids Stimulate SREBP2-Mediated Cholesterogenesis and Promote Non-Alcoholic Fatty Liver Disease

    Oteng, A-B., Loregger, A., van Weeghel, M., Zelcer, N. & Kersten, S., 2019, In: Molecular nutrition & food research. 1900385.

    Research output: Contribution to journalArticleAcademicpeer-review

  8. N-Glycosylation Defects in Humans Lower Low-Density Lipoprotein Cholesterol Through Increased Low-Density Lipoprotein Receptor Expression

    van den Boogert, M. A. W., Larsen, L. E., Ali, L., Kuil, S. D., Chong, P. L. W., Loregger, A., Kroon, J., Schnitzler, J. G., Schimmel, A. W. M., Peter, J., Levels, J. H. M., Steenbergen, G., Morava, E., Dallinga-Thie, G. M., Wevers, R. A., Kuivenhoven, J. A., Hand, N. J., Zelcer, N., Rader, D. J., Stroes, E. S. G., & 2 othersLefeber, D. J. & Holleboom, A. G., 2019, In: Circulation. 140, 4, p. 280-292

    Research output: Contribution to journalArticleAcademicpeer-review

  9. The E3 ubiquitin ligase inducible degrader of the LDL receptor/myosin light chain interacting protein in health and disease

    van Loon, N. M., Lindholm, D. & Zelcer, N., 2019, In: Current opinion in lipidology. 30, 3, p. 192-197

    Research output: Contribution to journalArticleAcademicpeer-review

  10. 2018
  11. IDOL in metabolic, neurodegenerative and cardiovascular disease

    van Loon, N. M., Rensen, P. C. N. & Zelcer, N., 2018, In: Aging. 10, 11, p. 3042-3043

    Research output: Contribution to journalEditorialAcademicpeer-review

  12. Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice

    van Loon, N. M., Ottenhoff, R., Kooijman, S., Moeton, M., Scheij, S., Roscam Abbing, R. L. P., Gijbels, M. J. J., Levels, J. H. M., Sorrentino, V., Berbée, J. F. P., Rensen, P. C. N. & Zelcer, N., 2018, In: Arteriosclerosis, thrombosis, and vascular biology. 38, 8, p. 1785-1795

    Research output: Contribution to journalArticleAcademicpeer-review

ID: 107375