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  1. 2023

  2. Sterol-regulated transmembrane protein TMEM86a couples LXR signaling to regulation of lysoplasmalogens in macrophages

    van Wouw, S. A. E., van den Berg, M., el Ouraoui, M., Meurs, A., Kingma, J., Ottenhoff, R., Loix, M., Hoeksema, M. A., Prange, K., Pasterkamp, G., Hendriks, J. J. A., Bogie, J. F. J., van Klinken, J. B., Vaz, F. M., Jongejan, A., de Winther, M. P. J. & Zelcer, N., 1 Feb 2023, In: Journal of lipid research. 64, 2, p. 100325 1 p., 100325.

    Research output: Contribution to journal › Article › Academic › peer-review

  3. 2022

  4. DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability

    Willemsen, L., Prange, K. H. M., Neele, A. E., van Roomen, C. P. A. A., Gijbels, M., Griffith, G. R., Toom, M. D., Beckers, L., Siebeler, R., Spann, N. J., Chen, H-J., Bosmans, L. A., Gorbatenko, A., van Wouw, S., Zelcer, N., Jacobs, H., van Leeuwen, F. & de Winther, M. P. J., 22 Nov 2022, In: Cell reports. 41, 8, 111703.

    Research output: Contribution to journal › Article › Academic › peer-review

  5. Proteolysis Targeting Chimeras (PROTACs): A Perspective on Integral Membrane Protein Degradation

    Ruffilli, C., Roth, S., Rodrigo, M., Boyd, H., Zelcer, N. & Moreau, K., 14 Oct 2022, In: ACS Pharmacology and Translational Science. 5, 10, p. 849-858 10 p.

    Research output: Contribution to journal › Review article › Academic › peer-review

  6. Anti-Galectin-2 Antibody Treatment Reduces Atherosclerotic Plaque Size and Alters Macrophage Polarity

    Kane, J., Jansen, M., Hendrix, S., Bosmans, L. A., Beckers, L., Tiel, C. V., Gijbels, M., Zelcer, N., Vries, C. J. D., von Hundelshausen, P., Vervloet, M., Eringa, E., Horrevoets, A. J., Royen, N. V. & Lutgens, E., 1 Jun 2022, In: Thrombosis and haemostasis. 122, 6, p. 1047-1057 11 p.

    Research output: Contribution to journal › Article › Academic › peer-review

  7. Defective Lipid Droplet–Lysosome Interaction Causes Fatty Liver Disease as Evidenced by Human Mutations in TMEM199 and CCDC115

    Larsen, L. E., van den Boogert, M. A. W., Rios-Ocampo, W. A., Jansen, J. C., Conlon, D., Chong, P. L. E., Levels, J. H. M., Eilers, R. E., Sachdev, V. V., Zelcer, N., Raabe, T., He, M., Hand, N. J., Drenth, J. P. H., Rader, D. J., Stroes, E. S. G., Lefeber, D. J., Jonker, J. W. & Holleboom, A. G., 1 Jan 2022, In: Cellular and molecular gastroenterology and hepatology. 13, 2, p. 583-597 15 p.

    Research output: Contribution to journal › Article › Academic › peer-review

  8. 2021

  9. Liver X receptor beta deficiency attenuates autoimmune-associated neuroinflammation in a T cell-dependent manner

    Bogie, J. F. J., Vanmierlo, T., Vanmol, J., Timmermans, S., Mailleux, J., Nelissen, K., Wijnands, E., Wouters, K., Stinissen, P., Gustafsson, J-Å., Steffensen, K. R., Mulder, M., Zelcer, N. & Hendriks, J. J. A., 1 Nov 2021, In: Journal of autoimmunity. 124, 102723.

    Research output: Contribution to journal › Article › Academic › peer-review

  10. Four-and-a-half LIM domain protein 2 (FHL2) deficiency protects mice from diet-induced obesity and high FHL2 expression marks human obesity

    Clemente-Olivo, M. P., Habibe, J. J., Vos, M., Ottenhoff, R., Jongejan, A., Herrema, H., Zelcer, N., Kooijman, S., Rensen, P. C. N., van Raalte, D. H., Nieuwdorp, M., Eringa, E. C. & de Vries, C. J., 1 Aug 2021, In: Metabolism: clinical and experimental. 121, 154815.

    Research output: Contribution to journal › Article › Academic › peer-review

  11. 2020

  12. Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism

    Loregger, A., Raaben, M., Nieuwenhuis, J., Tan, J. M. E., Jae, L. T., van den Hengel, L. G., Hendrix, S., van den Berg, M., Scheij, S., Song, J-Y., Huijbers, I. J., Kroese, L. J., Ottenhoff, R., van Weeghel, M., van de Sluis, B., Brummelkamp, T. & Zelcer, N., 1 Dec 2020, In: Nature communications. 11, 1, 1128.

    Research output: Contribution to journal › Article › Academic › peer-review

  13. Regulation of intestinal LDLR by the LXR-IDOL axis

    van Loon, N. M., van Wouw, S. A. E., Ottenhoff, R., Nelson, J. K., Kingma, J., Scheij, S., Moeton, M. & Zelcer, N., 1 Dec 2020, In: Atherosclerosis. 315, p. 1-9 9 p.

    Research output: Contribution to journal › Article › Academic › peer-review

  14. Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site

    Martinelli, L., Adamopoulos, A., Johansson, P., Wan, P. T., Gunnarsson, J., Guo, H., Boyd, H., Zelcer, N. & Sixma, T. K., 25 Sep 2020, In: Journal of biological chemistry. 295, 39, p. 13570-13583 14 p.

    Research output: Contribution to journal › Article › Academic › peer-review

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