Research interests

* Contribution of the LXR-IDOL-LDLR axis to cholesterol metabolism

* Identification of novel metabolic genes

* Studying the contribution of the UPS system to metabolism

specialisation

Transcriptional regulation of metabolism

Research output

  1. Identification of a loss-of-function inducible degrader of the low-density lipoprotein receptor variant in individuals with low circulating low-density lipoprotein

    Research output: Contribution to journal › Article › Academic › peer-review

  2. The Deubiquitylase USP2 Regulates the LDLR Pathway by Counteracting the E3-Ubiquitin Ligase IDOL

    Research output: Contribution to journal › Article › Academic › peer-review

  3. Identification of the (Pro)renin Receptor as a Novel Regulator of Low-Density Lipoprotein Metabolism

    Research output: Contribution to journal › Article › Academic › peer-review

  4. The E3 ubiquitin ligase MARCH6 degrades squalene monooxygenase and affects 3-hydroxy-3-methyl-glutaryl coenzyme A reductase and the cholesterol synthesis pathway

    Research output: Contribution to journal › Article › Academic › peer-review

  5. LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor

    Research output: Contribution to journal › Article › Academic › peer-review

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Projects

  1. Zelcer N.: Transcriptional regulation of metabolism

    Project: Research

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ID: 107375