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Main research focus is on Tissue Spectroscopy, Spectroscopic Imaging, Fluorescence Diagnostics and PhotoDynamic Therapy (PDT) of tumours. We have a strong collaboration with the 'van 't Hoff institute for molecular sciences' and the Chinese Academy of sciences to work on clinical applications of upconversion nanoparticles. In addition, a new field of research, the use of optical techniques for forensic investigations, is being explored. The forensic research group has strong collaborations with the Netherlands Forensics Institute and Forensic investigators of regional police. Subjects are; aging of bruises to improve the diagnosis of child abuse, detection of minimal traces at the crime scene, Localization, analysis and aging of bloodstains.