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There is an acute need for the development and implementation of valid research methods in child health clinical research. The major medical journals call for improved design, conduct and reporting of pediatric clinical trials. The Department of Pediatric Clinical Epidemiology KEK enhances the quantity and quality of clinical research in pediatrics, which, eventually, will lead to expansion of the body of evidence underlying clinical decision-making in pediatrics, and improved care for sick children.

KEK's mission is to improve the health of children by development and application of innovative methods needed to deliver the hospital's agenda of high quality translational, clinical, and health outcome research. KEK enhances the quantity and quality of this research locally, nationally and internationally, by offering specific modern methodological tools and hands-on expertise in the design, conduct and reporting of clinical research with children.

Our main research line is focused on innovative methodologies that enhance the quality and feasibility of child health clinical trials: (a) efficient sample size determination, (b) ethical issues around recruitment and safety of children in trials including Data Monitoring Committees' responsibilities , (c) development and evaluation of valid, age-adequate outcome measurement instruments.

Goals and ambition 2011-2013: (a) implement the highest methodological standards that KEK develops within international consortia in our local translational and clinical research, (b) train high potentials to become accomplished clinician-scientist leaders.