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Medical Biochemistry
- QR180 Immunology - genetic variation, macrophages, atherosclerosis, enhancers, transcription factors
Research areas
specialisation
Macrophages, regulation of gene expression, enhancer function, atherosclerosis.
Research interests
My research focusses on the transcriptional and epigenetic regulation of macrophages in health and (inflammatory or cardiovascular) disease. In particular, I am interested how gene enhancers function: which transcriptional regulators activate enhancers when macrophages are exposed to disease-associated signals, what genetic variants affect enhancer activity and how does this in turn result in differential gene expression?
ID: 60905