Research interests

Reciprocal interactions between coagulation and inflammation in the context of kidney diseases.

Current research programmes:

  1. The fibrinolytic system in renal disease
  2. Active Protein C (APC) and the endothelial protein C receptor (EPCR) in acute kidney injury and renal allograft rejection
  3. APC and EPCR in antiphospholipid antibody-induced renal thrombotic microangiopathy
  4. Platelets and platelet-derived microparticles (PMP) in acute kidney injury and renal allograft rejection

specialisation

Pathologist

Research output

  1. Release of extracellular DNA influences renal ischemia reperfusion injury by platelet activation and formation of neutrophil extracellular traps

    Research output: Contribution to journal › Article › Academic › peer-review

  2. Renal endothelial protein C receptor expression and shedding during diabetic nephropathy

    Research output: Contribution to journal › Article › Academic › peer-review

  3. Renal and urinary levels of endothelial protein C receptor correlate with acute renal allograft rejection

    Research output: Contribution to journal › Article › Academic › peer-review

  4. Activated protein C protects against renal ischaemia/reperfusion injury, independent of its anticoagulant properties

    Research output: Contribution to journal › Article › Academic › peer-review

  5. Mitochondrial DNA is Released in Urine of SIRS Patients With Acute Kidney Injury and Correlates With Severity of Renal Dysfunction

    Research output: Contribution to journal › Article › Academic › peer-review

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Projects

  1. Florquin S.: Renal inflammation and repair

    Project: Research

  2. Roelofs J.J.T.H.: [NO DATA]

    Project: Research

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ID: 81207