General Internal Medicine

Contact

Research interests

Intestinal homeostasis. Stem cell biology, tumor genetics, Translational control in the intestine. infections in immunocompromised patients. 

specialisation

internal medicine with subspecialisations acute medicine and hematology.

Research output

  1. Driver mutations of the adenoma-carcinoma sequence govern the intestinal epithelial global translational capacity

    Research output: Contribution to journal › Article › Academic › peer-review

  2. ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response

    Research output: Contribution to journal › Article › Academic › peer-review

  3. Expression of UPR effector proteins ATF6 and XBP1 reduce colorectal cancer cell proliferation and stemness by activating PERK signaling

    Research output: Contribution to journal › Article › Academic › peer-review

  4. Heterozygosity of chaperone GRP78 reduces intestinal stem cell regeneration potential and protects against adenoma formation

    Research output: Contribution to journal › Article › Academic › peer-review

  5. Induction of endoplasmic reticulum stress by deletion of Grp78 depletes Apc mutant intestinal epithelial stem cells

    Research output: Contribution to journal › Article › Academic › peer-review

View all (60) »

Projects

  1. efficacy of plasma derived neutralizing antibodies in immunocompromized patients with COVID-19

    Project: Research

View all () »

ID: 59810