1. 2023
  2. C5 inhibitors are not C5a inhibitors

    Lim, E. H. T., Vlaar, A. P. J., de Bruin, S., Brouwer, M. C. & van de Beek, D., 29 Mar 2023, (E-pub ahead of print) In: Expert review of anti-infective therapy.

    Research output: Contribution to journalComment/Letter to the editorAcademic

  3. Cystic fibrosis transmembrane conductance regulator modulators attenuate platelet activation and aggregation in blood of healthy donors and COVID-19 patients

    Asmus, E., Karle, W., Brack, M. C., Wittig, C., Behrens, F., Reinshagen, L., Pfeiffer, M., Schulz, S., Mandzimba-Maloko, B., Erfinanda, L., Perret, P. L., Michalick, L., Smeele, P. J., Lim, E. H. T., van den Brom, C. E., Vonk, A. B. A., Kaiser, T., Suttorp, N., Hippenstiel, S., Sander, L. E., & 10 othersKurth, F., Rauch, U., Landmesser, U., Haghikia, A., Preissner, R., Bogaard, H. J., Witzenrath, M., Kuebler, W. M., Szulcek, R. & Simmons, S., 1 Mar 2023, In: European respiratory journal. 61, 3, 2202009.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. 2022
  5. Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial

    Vlaar, A. P. J., Witzenrath, M., van Paassen, P., Heunks, L. M. A., Mourvillier, B., de Bruin, S., Lim, E. H. T., Brouwer, M. C., Tuinman, P. R., Saraiva, J. F. K., Marx, G., Lobo, S. M., Boldo, R., Simon-Campos, J. A., Cornet, A. D., Grebenyuk, A., Engelbrecht, J. M., Mukansi, M., Jorens, P. G., Zerbib, R., & 7 othersRückinger, S., Pilz, K., PANAMO study group, Guo, R., van de Beek, D., Riedemann, N. C. & van Amstel, R. B. E., 1 Dec 2022, In: lancet. Respiratory medicine. 10, 12, p. 1137-1146 10 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  6. Anti-C5a antibody vilobelimab treatment and the effect on biomarkers of inflammation and coagulation in patients with severe COVID-19: a substudy of the phase 2 PANAMO trial

    Lim, E. H. T., Vlaar, A. P. J., Bos, L. D. J., van Vught, L. A., Boer, A. M. T., Dujardin, R. W. G., Habel, M., Xu, Z., Brouwer, M. C., van de Beek, D., de Bruin, S., the Amsterdam UMC COVID-19 Biobank Investigators, van Agtmael, M., Algera, A. G., Appelman, B., van Baarle, F., Beudel, M., Bogaard, H. J., Bomers, M., Bonta, P., & 63 othersBotta, M., de Brabander, J., Bree, G., Bugiani, M., Bulle, E., Chouchane, O., Cloherty, A., Buis, D. T. P., de Rotte, M. C. F. J., Dijkstra, M., Dongelmans, D. A., Elbers, P., Fleuren, L., Geerlings, S., Geijtenbeek, T., Girbes, A., Goorhuis, B., Grobusch, M. P., Hagens, L., Hamann, J., Harris, V., Hemke, R., Hermans, S. M., Heunks, L., Hollmann, M., Horn, J., Hovius, J. W., de Jong, M. D., Koning, R., van Mourik, N., Nellen, J., Nossent, E. J., Paulus, F., Peters, E., Piña-Fuentes, D. A. I., van der Poll, T., Preckel, B., Prins, J. M., Raasveld, J., Reijnders, T., Schinkel, M., Schrauwen, F. A. P., Schultz, M. J., Schuurman, A., Schuurmans, J., Sigaloff, K., Slim, M. A., Smeele, P., Smit, M., Stijnis, C. S., Stilma, W., Teunissen, C., Thoral, P., Tsonas, A. M., Tuinman, P. R., van der Valk, M., Veelo, D., Volleman, C., de Vries, H., van Vugt, M., Wouters, D., Zwinderman, A. H. & Wiersinga, W. J., 1 Dec 2022, In: Respiratory research. 23, 1, 6 p., 375.

    Research output: Contribution to journalArticleAcademicpeer-review

  7. EXpert consensus On Diaphragm UltraSonography in the critically ill (EXODUS): a Delphi consensus statement on the measurement of diaphragm ultrasound-derived parameters in a critical care setting

    Haaksma, M. E., Smit, J. M., Boussuges, A., Demoule, A., Dres, M., Ferrari, G., Formenti, P., Goligher, E. C., Heunks, L., Lim, E. H. T., Mokkink, L. B., Soilemezi, E., Shi, Z., Umbrello, M., Vetrugno, L., Vivier, E., Xu, L., Zambon, M. & Tuinman, P. R., 1 Dec 2022, In: Critical Care. 26, 1, 99.

    Research output: Contribution to journalArticleAcademicpeer-review

  8. Complement activation in COVID-19 and targeted therapeutic options: A scoping review

    Lim, E. H. T., van Amstel, R. B. E., de Boer, V. V., van Vught, L. A., de Bruin, S., Brouwer, M. C., Vlaar, A. P. J. & van de Beek, D., 30 Jul 2022, (E-pub ahead of print) In: Blood reviews. 100995.

    Research output: Contribution to journalReview articleAcademicpeer-review

  9. Neurofilament light increases over time in severe COVID-19 and is associated with delirium

    Smeele, P. J., Vermunt, L., Blok, S., Duitman, J. W., Nossent, E. J., van Agtmael, M. A., Heunks, L. M. A., Horn, J., Bogaard, H. J., Teunissen, C. E., Amsterdam UMC COVID-19 Biobank, van Agtmael, M., Algera, A. G., Appelman, B., van Baarle, F., Bax, D., Beudel, M., Bomers, M., Bonta, P., Bos, L., & 72 othersBotta, M., de Brabander, J., de Bree, G., de Bruin, S., Buis, D. T. P., Bugiani, M., Bulle, E., Chekrouni, N., Chouchane, O., Cloherty, A., Dijkstra, M., Dongelmans, D. A., Duijvelaar, E., Dujardin, R. W. G., Elbers, P., Fleuren, L., Geerlings, S., Geijtenbeek, T., Girbes, A., Goorhuis, B., Grobusch, M. P., Hafkamp, F., Hagens, L., Hamann, J., Harris, V., Hemke, R., Hermans, S. M., Heunks, L., Hollmann, M., Hovius, J. W., de Jong, M. D., Koning, R., Lim, E. H. T., van Mourik, N., Nellen, J., Olie, S., Paulus, F., Peters, E., Pina-Fuentes, D. A. I., van der Poll, T., Preckel, B., Raasveld, J., Reijnders, T., de Rotte, M. C. F. J., Schippers, J. R., Schinkel, M., Schultz, M. J., Schrauwen, F. A. P., Schuurman, A., Schuurmans, J., Sigaloff, K., Slim, M. A., Smeele, P., Smit, M., Stijnis, C. S., Stilma, W., Thoral, P., Tsonas, A. M., Tuinman, P. R., van der Valk, M., Veelo, D., Volleman, C., de Vries, H., Vught, L. A., van Vugt, M., Wouters, D., Zwinderman, A. H., Brouwer, M. C., Wiersinga, W. J., Vlaar, A. P. J., van de Beek, D. & Teunissen, C. E., 26 Jul 2022, In: Brain Communications. 4, 4, fcac195.

    Research output: Contribution to journalArticleAcademicpeer-review

  10. The anti-C5a antibody vilobelimab efficiently inhibits C5a in patients with severe COVID-19

    Vlaar, A. P. J., Lim, E. H. T., de Bruin, S., Rückinger, S., Pilz, K., Brouwer, M. C., Guo, R-F., Heunks, L. M. A., Busch, M. H., van Paassen, P., Riedemann, N. C. & van de Beek, D., Apr 2022, In: CTS-CLINICAL AND TRANSLATIONAL SCIENCE. 15, 4, p. 854-858 5 p.

    Research output: Contribution to journalArticleAcademicpeer-review

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