Research interests

Our research is centered around the cellular and pathophysiological functions of P4 ATPases, lipid flippases that are implicated in the biogenesis of transport vesicles. Genome-wide association studies predict a role for various P4 ATPases as predisposing factors in complex diseases, including atherosclerosis, rheumatoid arthritis, type 2 diabetes and Alzheimer’s disease. It is our goal to delineate the role of P4 ATPases in aforementioned diseases.

specialisation

Biochemistry, cell biology, phospholipid transport, Hepatobiliary transport, cholestasis

Research output

  1. Therapeutic base editing in the adult liver

    Research output: Contribution to journalArticleAcademicpeer-review

  2. Collagen release by human hepatic stellate cells requires vitamin C and is efficiently blocked by hydroxylase inhibition

    Research output: Contribution to journalArticleAcademicpeer-review

  3. REPLY:

    Research output: Contribution to journalComment/Letter to the editorAcademic

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