Research interests

Our primary goal is to pioneer novel immune based preventive and curative interventions in oncology, as we strongly believe that prevention and cure are better than any palliative treatment. Our research focusses on the application of T-cell induction in prophylactic and curative oncologic treatment settings, targeting tumour specific neo-antigens. Among other activities, this involves the search for neo-antigens in mismatch repair deficient colorectal cancer patients. For that purpose my group leads a KWF granted consortium and a clinical trial sponsored by pharma . In addition my research group explores novel ways to combine ICB treatment with radiotherapy , also in the context of investigator initiated a clinical trials.

specialisation

Medical oncology, immuno oncology

Research output

  1. Rapid DNA vaccination against Burkholderia pseudomallei flagellin by tattoo or intranasal application

    Research output: Contribution to journalArticleAcademicpeer-review

  2. A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Rapid outer-surface protein C DNA tattoo vaccination protects against Borrelia afzelii infection

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Visualization of immediate immune responses to pioneer metastatic cells in the lung

    Research output: Contribution to journalArticleAcademicpeer-review

  5. In vivo antigen stability affects DNA vaccine immunogenicity

    Research output: Contribution to journalArticleAcademicpeer-review

View all (36) »

ID: 42206